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NCT06613100 · ClinicalTrials.gov registry record · Phase 1

Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

A Phase 1 study of Prostate Cancer, sponsored by Amgen.

Recruiting
Registry status
Phase 1
Development phase
40
Enrollment target
8
Study locations

NCT06613100 is a Phase 1 study of Prostate Cancer that is actively recruiting participants, run by Amgen. The registered enrollment target is 40 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (93% lower). The trial reports 8 study locations across 7 states.

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The verdict

NCT06613100, a Phase 1 study of Prostate Cancer, is actively recruiting participants, sponsored by Amgen.

RECRUITING
Registry status
Phase 1
Development phase
40 participants
Enrollment target
8
Study locations

Study Summary

The primary objectives of this study are to evaluate the safety and tolerability of xaluritamig administered as monotherapy or in combination with an oral Gonadotropin-releasing Hormone (GnRH) antagonist in the neoadjuvant setting followed by radical prostatectomy, and to evaluate the feasibility and safety of a radical prostatectomy following xaluritamig administered as monotherapy or in combination with an oral GnRH antagonist in the neoadjuvant setting.

Conditions Studied

Interventions

  • DRUG Xaluritamig
  • DRUG GnRH Antagonist

Study Locations (8)

Other

  • Universitaetsklinikum Essen - Essen
  • Universitaetsklinikum Hamburg Eppendorf - Hamburg

California

  • University of California San Francisco - San Francisco

Missouri

  • Washington University - St Louis

Ohio

  • The Ohio State University - Columbus

Pennsylvania

  • Thomas Jefferson University - Philadelphia

Washington

  • Fred Hutchinson Cancer Center - Seattle

Wisconsin

  • Medical College of Wisconsin - Milwaukee

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2024-11-25
Est. Completion 2030-01-23
Phase Phase 1

Sponsor

Amgen

558 total trials

What the Registry Record Tells You About NCT06613100

The ClinicalTrials.gov registry entry for NCT06613100 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (93% lower). The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 2 interventions - of which Xaluritamig is the first listed.

NCT06613100 reports 8 study locations spanning 7 distinct geographic areas - top geographies include Other, California, Missouri.

Frequently Asked Questions

What is clinical trial NCT06613100 about?

NCT06613100 is a clinical study titled "Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer". The primary objectives of this study are to evaluate the safety and tolerability of xaluritamig administered as monotherapy or in combination with an oral Gonadotropin-releasing Hormone (GnRH) antagonist in the neoadjuvant setting followed by radical prostatectomy, and to evaluate the feasibility an...

What is the current status of trial NCT06613100?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2024-11-25. Estimated completion is 2030-01-23.

What conditions does trial NCT06613100 study?

This clinical trial studies the following conditions: Prostate Cancer.

What interventions are being tested in trial NCT06613100?

The interventions under investigation include: Xaluritamig (DRUG), GnRH Antagonist (DRUG).

Who is sponsoring clinical trial NCT06613100?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06613100 being conducted?

This trial has 8 study locations across California, Missouri, Ohio, Pennsylvania, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.