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NCT06594991 · ClinicalTrials.gov registry record · Phase 2
A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma
A Phase 2 study of Advanced Melanoma, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 88
- Enrollment target
- 11
- Study locations
NCT06594991 is a Phase 2 study of Advanced Melanoma that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 88 participants, below the 168-participant average among 21 other Advanced Melanoma trials with a reported enrollment target (48% lower). The trial reports 11 study locations across 4 states.
The verdict
NCT06594991, a Phase 2 study of Advanced Melanoma, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 88 participants
- Enrollment target
- 11
- Study locations
Study Summary
The purpose of this study is to test whether the combination of fianlimab, cemiplimab, and ipilimumab is a safe and effective treatment that causes few or mild side effects for locally advanced or metastatic, unresectable, refractory melanoma.
Conditions Studied
Interventions
- DRUG Cemiplimab
- DRUG Ipilimumab
- DRUG Fianlimab
Study Locations (11)
New Jersey
- Memorial Sloan Kettering Basking Ridge (All Protocol Activities) - Basking Ridge
- Hackensack Meridian Health (Data Collection Only) - Hackensack
- Memorial Sloan Kettering Monmouth (All Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale
New York
- Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (All Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) - Uniondale
California
- Cedars-Sinai Medical Center - Los Angeles
- Stanford University (Data Collection Only) - Stanford
Texas
- MD Anderson Cancer Center (Data Collection Only) - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2024-09-10 |
| Est. Completion | 2027-09 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06594991
The ClinicalTrials.gov registry entry for NCT06594991 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 168-participant average among 21 other Advanced Melanoma trials with a reported enrollment target (48% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Advanced Melanoma appearing as the primary indexed condition, and to 3 interventions - of which Cemiplimab is the first listed.
NCT06594991 reports 11 study locations spanning 4 distinct geographic areas - top geographies include New Jersey, New York, California.
Frequently Asked Questions
What is clinical trial NCT06594991 about?
NCT06594991 is a clinical study titled "A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma". The purpose of this study is to test whether the combination of fianlimab, cemiplimab, and ipilimumab is a safe and effective treatment that causes few or mild side effects for locally advanced or metastatic, unresectable, refractory melanoma.
What is the current status of trial NCT06594991?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 88 participants. The study started on 2024-09-10. Estimated completion is 2027-09.
What conditions does trial NCT06594991 study?
This clinical trial studies the following conditions: Advanced Melanoma.
What interventions are being tested in trial NCT06594991?
The interventions under investigation include: Cemiplimab (DRUG), Ipilimumab (DRUG), Fianlimab (DRUG).
Who is sponsoring clinical trial NCT06594991?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06594991 being conducted?
This trial has 11 study locations across California, New Jersey, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.