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NCT06582888 · ClinicalTrials.gov registry record · Early Phase 1

Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder

A Early Phase 1 study of Nicotine Addiction and Craving, sponsored by University of California, San Diego.

Recruiting
Registry status
Early Phase 1
Development phase
200
Enrollment target
1
Study location

NCT06582888 is a Early Phase 1 study of Nicotine Addiction and Craving that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 200 participants, below the 704-participant average among 10 other Nicotine Addiction trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06582888, a Early Phase 1 study of Nicotine Addiction and Craving, is actively recruiting participants, sponsored by University of California, San Diego.

RECRUITING
Registry status
Early Phase 1
Development phase
200 participants
Enrollment target
1
Study location

Study Summary

The proposed project will include enrollment of 200 daily tobacco cigarette users, ages 22+, from the San Diego community. Participants will be assessed on the VR Nicotine Cue Exposure paradigm then randomized (stratified on age and sex) to receive varenicline (target dose 1mg twice daily) or placebo (n per group=100; total N=200). Following eight days of titration, participants will be assessed again on the VR Nicotine Cue Exposure paradigm. They will then be followed via mobile assessments for eight days on target dose of varenicline, and 30-days post assessment by phone, to assess short-term nicotine use behaviors.

Interventions

  • DRUG Placebo
  • DRUG Varenicline Tartrate

Study Locations (1)

California

  • University California, San Diego - San Diego

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2024-11-19
Est. Completion 2028-08-15
Phase Early Phase 1

Sponsor

University of California, San Diego

775 total trials

What the Registry Record Tells You About NCT06582888

The ClinicalTrials.gov registry entry for NCT06582888 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 704-participant average among 10 other Nicotine Addiction trials with a reported enrollment target (72% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Nicotine Addiction appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06582888 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06582888 about?

NCT06582888 is a clinical study titled "Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder". The proposed project will include enrollment of 200 daily tobacco cigarette users, ages 22+, from the San Diego community. Participants will be assessed on the VR Nicotine Cue Exposure paradigm then randomized (stratified on age and sex) to receive varenicline (target dose 1mg twice daily) or placeb...

What is the current status of trial NCT06582888?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 200 participants. The study started on 2024-11-19. Estimated completion is 2028-08-15.

What conditions does trial NCT06582888 study?

This clinical trial studies the following conditions: Nicotine Addiction, Craving.

What interventions are being tested in trial NCT06582888?

The interventions under investigation include: Placebo (DRUG), Varenicline Tartrate (DRUG).

Who is sponsoring clinical trial NCT06582888?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06582888 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.