Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06559215 · ClinicalTrials.gov registry record · Phase 2
Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
A Phase 2 study of Pain, Postoperative and Analgesia, sponsored by Texas Scottish Rite Hospital for Children.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06559215: Recruiting Phase 2 study of Pain, Postoperative and Analgesia, sponsored by Texas Scottish Rite Hospital for Children.
NCT06559215 is a Phase 2 study of Pain, Postoperative and Analgesia that is actively recruiting participants, run by Texas Scottish Rite Hospital for Children. The registered enrollment target is 100 participants, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06559215, a Phase 2 study of Pain, Postoperative and Analgesia, is actively recruiting participants, sponsored by Texas Scottish Rite Hospital for Children.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients provides significant pain relief and decreased narcotic use. The main questions it aims to answer are: * Does Exparel significantly reduce Visual Analog Scale (VAS) pain scores and pain levels up to one week postoperatively? * Does Exparel significantly decrease narcotic use (number of pills taken) up to one week postoperatively? Researchers will compare the pain outcomes and narcotic use of patients who receive Exparel and Marcaine via local infiltration to those of patients who receive only Marcaine via local infiltration for their MPFL reconstruction surgery. The goal is to understand if there is a significant difference in patient pain outcomes and narcotic use outside the first 24 hours postoperatively. Participants will: * receive either Exparel + Marcaine intraoperatively or Marcaine only intraoperatively during their MPFL reconstruction surgery * receive and complete questionnaires at postoperative days 1, 4, and 7 regarding their pain scores, levels, and outcomes, effective pain treatments, overall pain interference, narcotic use (number of pills taken), and overall pain treatment satisfaction * receive and complete secondary outcome measures of functional and psychological outcomes regarding their MPFL reconstruction surgery at postoperative day 1
Primary Outcome
Scale with evocative faces from 0-10 (0 = No Pain, 10 = Worst Pain Possible) that assists children in communicating about their pain
Conditions Studied
Interventions
- DRUG Exparel
Study Locations (1)
Texas
- Texas Scottish Rite Hospital for Children - Frisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-12-01 |
| Est. Completion | 2028-09 |
| Phase | Phase 2 |
What NCT06559215 shows while recruiting
NCT06559215 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (63% lower).
The record links to 4 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 1 intervention - of which Exparel is the first listed.
NCT06559215 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06559215 about?
NCT06559215 is a clinical study titled "Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population". The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients provides significant pain relief and decreased narcotic use. The main q...
What is the current status of trial NCT06559215?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2025-12-01. Estimated completion is 2028-09.
What conditions does trial NCT06559215 study?
This clinical trial studies the following conditions: Pain, Postoperative, Analgesia, Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children.
What interventions are being tested in trial NCT06559215?
The interventions under investigation include: Exparel (DRUG).
Who is sponsoring clinical trial NCT06559215?
This trial is sponsored by Texas Scottish Rite Hospital for Children, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06559215 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Postoperative
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06559215's enrollment target sits among peer trials
100 44th of 113 higher than 67 of 113 other Pain, Postoperative trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
RECRUITING · Phase 2
-
Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children
RECRUITING · Phase 2
-
Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement
ACTIVE NOT RECRUITING · Phase 2
-
Intraoperative Liposomal Bupivacaine vs. Bupivacaine for Total Hip Replacement Pain Management
COMPLETED · Phase 2
-
Clinical Proposal for the Comparison of Intraperitoneal Anesthetic to Injected Local Anesthetic
COMPLETED · Phase 2
-
Perioperative Pregabalin in Ureteroscopy
COMPLETED · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI