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RECRUITING Phase 1

Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome

NCT06502145 · View on ClinicalTrials.gov ↗

Study Summary

This is a phase I study with a primary objective of determining the recommended phase II dose of iadademstat with azacitidine in adult subjects with myelodysplastic syndrome (MDS).

Conditions Studied

Interventions

  • DRUG Azacitidine Level -1
  • DRUG Azacitidine Level 0
  • DRUG Azacitidine Level 1
  • DRUG Iadademstat Level -1
  • DRUG Iadademstat Level 0

Study Locations (1)

Wisconsin

  • Froedtert Hospital & the Medical College of Wisconsin — Milwaukee

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2025-01-10
Est. Completion 2027-10
Phase Phase 1

Sponsor

Medical College of Wisconsin

614 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06502145

The ClinicalTrials.gov registry entry for NCT06502145 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical College of Wisconsin, which has 614 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Myelodysplastic Syndromes appearing as the primary indexed condition, and to 5 interventions — of which Azacitidine Level -1 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06502145 reports 1 study location spanning 1 distinct geographic area — top geographies include Wisconsin. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06502145 about?

NCT06502145 is a clinical study titled "Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome". This is a phase I study with a primary objective of determining the recommended phase II dose of iadademstat with azacitidine in adult subjects with myelodysplastic syndrome (MDS).

What is the current status of trial NCT06502145?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2025-01-10. Estimated completion is 2027-10.

What conditions does trial NCT06502145 study?

This clinical trial studies the following conditions: Myelodysplastic Syndromes. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06502145?

The interventions under investigation include: Azacitidine Level -1 (DRUG), Azacitidine Level 0 (DRUG), Azacitidine Level 1 (DRUG), Iadademstat Level -1 (DRUG), Iadademstat Level 0 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06502145?

This trial is sponsored by Medical College of Wisconsin, which has 614 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06502145 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial