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NCT06502145 · ClinicalTrials.gov registry record · Phase 1

Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome

A Phase 1 study of Myelodysplastic Syndromes, sponsored by Medical College of Wisconsin.

Recruiting
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT06502145 is a Phase 1 study of Myelodysplastic Syndromes that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 12 participants, below the 285-participant average among 173 other Myelodysplastic Syndromes trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06502145, a Phase 1 study of Myelodysplastic Syndromes, is actively recruiting participants, sponsored by Medical College of Wisconsin.

RECRUITING
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

This is a phase I study with a primary objective of determining the recommended phase II dose of iadademstat with azacitidine in adult subjects with myelodysplastic syndrome (MDS).

Conditions Studied

Interventions

  • DRUG Azacitidine Level -1
  • DRUG Azacitidine Level 0
  • DRUG Azacitidine Level 1
  • DRUG Iadademstat Level -1
  • DRUG Iadademstat Level 0

Study Locations (1)

Wisconsin

  • Froedtert Hospital & the Medical College of Wisconsin - Milwaukee

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2025-01-10
Est. Completion 2027-10
Phase Phase 1

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT06502145

The ClinicalTrials.gov registry entry for NCT06502145 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 285-participant average among 173 other Myelodysplastic Syndromes trials with a reported enrollment target (96% lower). The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Myelodysplastic Syndromes appearing as the primary indexed condition, and to 5 interventions - of which Azacitidine Level -1 is the first listed.

NCT06502145 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT06502145 about?

NCT06502145 is a clinical study titled "Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome". This is a phase I study with a primary objective of determining the recommended phase II dose of iadademstat with azacitidine in adult subjects with myelodysplastic syndrome (MDS).

What is the current status of trial NCT06502145?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2025-01-10. Estimated completion is 2027-10.

What conditions does trial NCT06502145 study?

This clinical trial studies the following conditions: Myelodysplastic Syndromes.

What interventions are being tested in trial NCT06502145?

The interventions under investigation include: Azacitidine Level -1 (DRUG), Azacitidine Level 0 (DRUG), Azacitidine Level 1 (DRUG), Iadademstat Level -1 (DRUG), Iadademstat Level 0 (DRUG).

Who is sponsoring clinical trial NCT06502145?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06502145 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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