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NCT06496178 · ClinicalTrials.gov registry record · Phase 3
A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients
A Phase 3 study of Head and Neck Squamous Cell Carcinoma, sponsored by Merus B.V..
- Recruiting
- Registry status
- Phase 3
- Development phase
- 500
- Enrollment target
- 20
- Study locations
NCT06496178 is a Phase 3 study of Head and Neck Squamous Cell Carcinoma that is actively recruiting participants, run by Merus B.V.. The registered enrollment target is 500 participants, above the 113-participant average among 124 other Head and Neck Squamous Cell Carcinoma trials with a reported enrollment target (342% higher). The trial reports 20 study locations across 9 states.
The verdict
NCT06496178, a Phase 3 study of Head and Neck Squamous Cell Carcinoma, is actively recruiting participants, sponsored by Merus B.V..
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 500 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a phase 3 open-label, randomized, controlled, multicenter study to compare petosemtamab vs investigator's choice monotherapy in HNSCC patients for the second- and third-line treatment of incurable metastatic/recurrent disease.
Conditions Studied
Interventions
- DRUG Petosemtamab
- DRUG Investigator's Choice
Study Locations (20)
California
- Site 82 - Duarte
- Site 25 - La Jolla
- Site 173 - Orange
- Site 28 - Palo Alto
- Site 127 - Sacramento
- Site 46 - San Francisco
Florida
- Site 12 - Fort Myers
- Site 123 - Jacksonville
- Site 9 - Orlando
- Site 138 - Tampa
Arizona
- Site 102 - Prescott
- Site 125 - Scottsdale
Georgia
- Site 187 - Atlanta
- Site 207 - Atlanta
Illinois
- Site 152 - Chicago
- Site 68 - Chicago
Alabama
- Site 160 - Mobile
Colorado
- Site 130 - Lone Tree
District of Columbia
- Site 104 - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 2024-06-25 |
| Est. Completion | 2029-03 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06496178
The ClinicalTrials.gov registry entry for NCT06496178 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 113-participant average among 124 other Head and Neck Squamous Cell Carcinoma trials with a reported enrollment target (342% higher). The listed sponsor is Merus B.V., which has 8 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Head and Neck Squamous Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Petosemtamab is the first listed.
NCT06496178 reports 20 study locations spanning 9 distinct geographic areas - top geographies include California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT06496178 about?
NCT06496178 is a clinical study titled "A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients". This is a phase 3 open-label, randomized, controlled, multicenter study to compare petosemtamab vs investigator's choice monotherapy in HNSCC patients for the second- and third-line treatment of incurable metastatic/recurrent disease.
What is the current status of trial NCT06496178?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 500 participants. The study started on 2024-06-25. Estimated completion is 2029-03.
What conditions does trial NCT06496178 study?
This clinical trial studies the following conditions: Head and Neck Squamous Cell Carcinoma.
What interventions are being tested in trial NCT06496178?
The interventions under investigation include: Petosemtamab (DRUG), Investigator's Choice (DRUG).
Who is sponsoring clinical trial NCT06496178?
This trial is sponsored by Merus B.V., which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06496178 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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