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NCT06456658 · ClinicalTrials.gov registry record · NA

Statin Reminders for Improving Prescribing in Primary Care

A NA study, sponsored by Vanderbilt University Medical Center.

Completed
Registry status
NA
Development phase
3,332
Enrollment target

NCT06456658: Completed NA study, sponsored by Vanderbilt University Medical Center.

NCT06456658 is a NA study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 3,332 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (137% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06456658, a NA study, has completed, sponsored by Vanderbilt University Medical Center.

COMPLETED
Registry status
NA
Development phase
3,332 participants
Enrollment target

Study Summary

Statins reduce cardiovascular events and mortality, but only 30% of eligible primary care patients nationally are on statins. Clinical decision support (CDS) interventions in the electronic health record (EHR) can deliver education to providers and increase adherence to guideline recommendations via many potential forms of delivery. Interruptive alerts are an effective form of CDS but disrupt clinician workflow and increase alert fatigue in an age of clinician burnout and frustration with the EHR. Non-interruptive reminders are proposed as an alternative method of delivering CDS; however, they require active pursuit by the provider, and their effectiveness compared to interruptive alerts has not been rigorously studied. The investigators propose a randomized trial comparing the effect of interruptive vs. non-interruptive reminders displayed to clinicians to increase statin prescribing in primary care clinics.

Primary Outcome

Statin prescription within 24 hours post-enrollment (either interruptive, non-interruptive, or silent/hidden reminder).

Interventions

  • OTHER Interruptive Reminder
  • OTHER Non-interruptive Reminder
  • OTHER No Reminder

Trial Details

FieldValue
Enrollment Target 3,332 participants
Start Date 2024-08-14
Est. Completion 2025-11-19
Phase NA

What the finished NCT06456658 record still lists

NCT06456658 is an interventional study that assigns participants to a tested intervention. Its 3,332 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (137% higher).

The record links to 0 conditions, and to 3 interventions - of which Interruptive Reminder is the first listed.

NCT06456658 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06456658 about?

NCT06456658 is a clinical study titled "Statin Reminders for Improving Prescribing in Primary Care". Statins reduce cardiovascular events and mortality, but only 30% of eligible primary care patients nationally are on statins. Clinical decision support (CDS) interventions in the electronic health record (EHR) can deliver education to providers and increase adherence to guideline recommendations via...

What is the current status of trial NCT06456658?

This trial is currently completed. It is a NA study. The enrollment target is 3,332 participants. The study started on 2024-08-14. Estimated completion is 2025-11-19.

What interventions are being tested in trial NCT06456658?

The interventions under investigation include: Interruptive Reminder (OTHER), Non-interruptive Reminder (OTHER), No Reminder (OTHER).

Who is sponsoring clinical trial NCT06456658?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06456658's enrollment target sits among peer trials

3,332 37th of 2000 higher than 1,964 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06456658, the US trial registry maintained by the National Library of Medicine. NCT06456658 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.