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NCT06390956 · ClinicalTrials.gov registry record · Phase 2

Pirtobrutinib in Combination With Rituximab in Adults With Untreated Marginal Zone Lymphoma (PIONEER-MZL)

A Phase 2 study of Marginal Zone Lymphoma, sponsored by University of Utah.

Recruiting
Registry status
Phase 2
Development phase
23
Enrollment target
2
Study locations

NCT06390956 is a Phase 2 study of Marginal Zone Lymphoma that is actively recruiting participants, run by University of Utah. The registered enrollment target is 23 participants, below the 102-participant average among 49 other Marginal Zone Lymphoma trials with a reported enrollment target (77% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06390956, a Phase 2 study of Marginal Zone Lymphoma, is actively recruiting participants, sponsored by University of Utah.

RECRUITING
Registry status
Phase 2
Development phase
23 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this clinical trial is to learn if the drugs Pirtobrutinib and Rituximab are effective for the treatment of newly diagnosed marginal zone lymphoma.

Conditions Studied

Marginal Zone Lymphoma

Interventions

  • DRUG Rituximab
  • DRUG Pirtobrutinib

Study Locations (2)

Missouri

  • Washington University - St Louis

Utah

  • Huntsman Cancer Institute at University of Utah - Salt Lake City

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2025-02-20
Est. Completion 2032-12
Phase Phase 2

Sponsor

University of Utah

818 total trials

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What the Registry Record Tells You About NCT06390956

The ClinicalTrials.gov registry entry for NCT06390956 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 102-participant average among 49 other Marginal Zone Lymphoma trials with a reported enrollment target (77% lower). The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Marginal Zone Lymphoma appearing as the primary indexed condition, and to 2 interventions - of which Rituximab is the first listed.

NCT06390956 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Missouri, Utah.

Frequently Asked Questions

What is clinical trial NCT06390956 about?

NCT06390956 is a clinical study titled "Pirtobrutinib in Combination With Rituximab in Adults With Untreated Marginal Zone Lymphoma (PIONEER-MZL)". The purpose of this clinical trial is to learn if the drugs Pirtobrutinib and Rituximab are effective for the treatment of newly diagnosed marginal zone lymphoma.

What is the current status of trial NCT06390956?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2025-02-20. Estimated completion is 2032-12.

What conditions does trial NCT06390956 study?

This clinical trial studies the following conditions: Marginal Zone Lymphoma.

What interventions are being tested in trial NCT06390956?

The interventions under investigation include: Rituximab (DRUG), Pirtobrutinib (DRUG).

Who is sponsoring clinical trial NCT06390956?

This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06390956 being conducted?

This trial has 2 study locations across Missouri, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.