Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 3

A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight

NCT06388187 · View on ClinicalTrials.gov ↗

Study Summary

This study will look at how well CagriSema helps people with excess body weight lose weight. CagriSema is a new medicine developed by Novo Nordisk that combines cagrilintide and semaglutide. CagriSema cannot yet be prescribed by doctors. In the study, participant will either get CagriSema or dummy medicine and which treatment participant get is decided by chance. The study will last for about 1½ years for each participant.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Semaglutide
  • DRUG Cagrilintide

Study Locations (20)

Other

  • Hospices Civils de Lyon-Hopital Lyon Sud-1 — Pierre-Bénite
  • Hospices Civils de Lyon-Hopital Lyon Sud — Pierre-Bénite
  • Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec — Saint-Herblain
  • Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil — Toulouse
  • InnoDiab Forschung GmbH — Essen
  • Wendisch - Dahl Hamburg - DZHW — Hamburg
  • AmBeNet GmbH — Leipzig
  • Institut für Diabetesforschung GmbH Münster - Dr. med. Rose — Münster
  • Forschungszentrum Ruhr KliFoCenter GmbH, Kahrmann — Witten
  • The Health Centre — Bradford-on-Avon

California

  • Aurora FDRC Inc. — Costa Mesa

Florida

  • Clinical Trial Res Assoc,Inc — Plantation

Indiana

  • Midwest Inst For Clin Res — Indianapolis

North Carolina

  • Accellacare — Wilmington

Texas

  • Velocity Clinical Res-Dallas — Dallas

Virginia

  • Washington Cntr Weight Mgmt — Arlington

Washington

  • Capital Clin Res Ctr,LLC — Olympia

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2024-06-24
Est. Completion 2026-04-21
Phase Phase 3

Sponsor

Novo Nordisk A/S

189 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06388187

The ClinicalTrials.gov registry entry for NCT06388187 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06388187 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Other, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06388187 about?

NCT06388187 is a clinical study titled "A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight". This study will look at how well CagriSema helps people with excess body weight lose weight. CagriSema is a new medicine developed by Novo Nordisk that combines cagrilintide and semaglutide. CagriSema cannot yet be prescribed by doctors. In the study, participant will either get CagriSema or dummy m...

What is the current status of trial NCT06388187?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 300 participants. The study started on 2024-06-24. Estimated completion is 2026-04-21.

What conditions does trial NCT06388187 study?

This clinical trial studies the following conditions: Obesity. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06388187?

The interventions under investigation include: Placebo (DRUG), Semaglutide (DRUG), Cagrilintide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06388187?

This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06388187 being conducted?

This trial has 20 study locations across California, Florida, Indiana, North Carolina, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial