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NCT06355778 · ClinicalTrials.gov registry record · NA
Adversity, Brain and Opioid Use Study
A NA study of Healthy and Opioid Use Disorder, sponsored by University of Michigan.
- Recruiting
- Registry status
- NA
- Development phase
- 185
- Enrollment target
- 1
- Study location
NCT06355778: Recruiting NA study of Healthy and Opioid Use Disorder, sponsored by University of Michigan.
NCT06355778 is a NA study of Healthy and Opioid Use Disorder that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 185 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06355778, a NA study of Healthy and Opioid Use Disorder, is actively recruiting participants, sponsored by University of Michigan.
- RECRUITING
- Registry status
- NA
- Development phase
- 185 participants
- Enrollment target
- 1
- Study location
Study Summary
The way people process and remember information may be related to adverse childhood experiences and Opioid Use Disorder symptoms. The purpose of this project is to examine brain function and performance during learning and memory tasks in adults. The study will compare measures of learning and memory across three groups of participants: those with an Opioid Use Disorder (OUD) that take buprenorphine for opioid replacement therapy, adults without an Opioid Use Disorder taking buprenorphine, and healthy adults that do not have an Opioid Use Disorder and are not taking buprenorphine.
Primary Outcome
BOLD signal during functional magnetic resonance imaging (fMRI) will be used as a measure of hippocampus activation when remembering common objects and scenes. The study team will examine differences between participants with Opioid Use Disorder (OUD) and those without OUD.
Conditions Studied
Interventions
- OTHER Magnetic Resonance Imaging (MRI)
- BEHAVIORAL Computer Tasks
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 185 participants |
| Start Date | 2025-01-09 |
| Est. Completion | 2028-04 |
| Phase | NA |
What NCT06355778 shows while recruiting
NCT06355778 is an interventional study that assigns participants to a tested intervention. The registered 185 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (71% lower).
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Magnetic Resonance Imaging (MRI) is the first listed.
NCT06355778 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT06355778 about?
NCT06355778 is a clinical study titled "Adversity, Brain and Opioid Use Study". The way people process and remember information may be related to adverse childhood experiences and Opioid Use Disorder symptoms. The purpose of this project is to examine brain function and performance during learning and memory tasks in adults. The study will compare measures of learning and memor...
What is the current status of trial NCT06355778?
This trial is currently recruiting. It is a NA study. The enrollment target is 185 participants. The study started on 2025-01-09. Estimated completion is 2028-04.
What conditions does trial NCT06355778 study?
This clinical trial studies the following conditions: Healthy, Opioid Use Disorder.
What interventions are being tested in trial NCT06355778?
The interventions under investigation include: Magnetic Resonance Imaging (MRI) (OTHER), Computer Tasks (BEHAVIORAL).
Who is sponsoring clinical trial NCT06355778?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06355778 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06355778's enrollment target sits among peer trials
185 131st of 1090 higher than 960 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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