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NCT04041154 · ClinicalTrials.gov registry record · NA
Behavioral and Neural Representations of Subjective Effort Cost
A NA study of Fatigue, sponsored by Hugo W. Moser Research Institute at Kennedy Krieger.
- Recruiting
- Registry status
- NA
- Development phase
- 185
- Enrollment target
- 1
- Study location
NCT04041154: Recruiting NA study of Fatigue, sponsored by Hugo W. Moser Research Institute at Kennedy Krieger.
NCT04041154 is a NA study of Fatigue that is actively recruiting participants, run by Hugo W. Moser Research Institute at Kennedy Krieger. The registered enrollment target is 185 participants, below the 217-participant average among 109 other Fatigue trials with a reported enrollment target (15% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04041154, a NA study of Fatigue, is actively recruiting participants, sponsored by Hugo W. Moser Research Institute at Kennedy Krieger.
- RECRUITING
- Registry status
- NA
- Development phase
- 185 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical effort value, and that fatigue and enhanced motivation will influence the subjective value of effort.
Primary Outcome
Choice data will be fit to a model of the form u(x) = x\^rho. The parameter rho is indicative of individuals' subjective preferences for effort. We will test if participants cognitive subjective effort parameters will be significantly different than zero. Effort levels will be expressed as a percentage of each individual's maximum exertion capacity. This will ensure that comparisons can be made between participants.
Conditions Studied
Interventions
- BEHAVIORAL Physical Fatigue
- BEHAVIORAL Cognitive Fatigue
- BEHAVIORAL Rewarding Stimuli
Study Locations (1)
Maryland
- Kennedy Krieger Institute - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 185 participants |
| Start Date | 2018-08-01 |
| Est. Completion | 2029-12-31 |
| Phase | NA |
What NCT04041154 shows while recruiting
NCT04041154 is an interventional study that assigns participants to a tested intervention. The registered 185 participants enrollment target is mid-sized for trials with a published cap, below the 217-participant average among 109 other Fatigue trials with a reported enrollment target (15% lower).
The record links to 1 condition, with Fatigue appearing as the primary indexed condition, and to 3 interventions - of which Physical Fatigue is the first listed.
NCT04041154 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04041154 about?
NCT04041154 is a clinical study titled "Behavioral and Neural Representations of Subjective Effort Cost". The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circu...
What is the current status of trial NCT04041154?
This trial is currently recruiting. It is a NA study. The enrollment target is 185 participants. The study started on 2018-08-01. Estimated completion is 2029-12-31.
What conditions does trial NCT04041154 study?
This clinical trial studies the following conditions: Fatigue.
What interventions are being tested in trial NCT04041154?
The interventions under investigation include: Physical Fatigue (BEHAVIORAL), Cognitive Fatigue (BEHAVIORAL), Rewarding Stimuli (BEHAVIORAL).
Who is sponsoring clinical trial NCT04041154?
This trial is sponsored by Hugo W. Moser Research Institute at Kennedy Krieger, which has 73 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04041154 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Fatigue
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04041154's enrollment target sits among peer trials
185 27th of 109 higher than 83 of 109 other Fatigue trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Fatigue trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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