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NCT06342024 · ClinicalTrials.gov registry record · NA
Pistachio Consumption on Inflammatory Markers and Lean Body Mass
A NA study of Inflammatory Response, sponsored by Virginia Polytechnic Institute and State University.
- Active
- Registry status
- NA
- Development phase
- 144
- Enrollment target
- 1
- Study location
NCT06342024: Active NA study of Inflammatory Response, sponsored by Virginia Polytechnic Institute and State University.
NCT06342024 is a NA study of Inflammatory Response that is active but no longer recruiting, run by Virginia Polytechnic Institute and State University. The registered enrollment target is 144 participants, below the 169-participant average among 16 other Inflammatory Response trials with a reported enrollment target (15% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06342024, a NA study of Inflammatory Response, is active but no longer recruiting, sponsored by Virginia Polytechnic Institute and State University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 144 participants
- Enrollment target
- 1
- Study location
Study Summary
Pistachio nuts (Pistacia vera L.) are a nutrient- and energy-dense food, and are a significant source of 15 different micronutrients. In addition to an excellent micronutrient profile, pistachios are a good source of monounsaturated and polyunsaturated fats (linoleic acid, oleic acid, and plant sterols). Pistachios have the lowest amount of total fat, and the highest protein, fiber, and phytosterol content compared to other nuts. They possess a high antioxidant content. Specifically, pistachios have high amounts of lutein, zeaxanthin, and phenolic compounds (e.g., anthocyanins, flavonoids, and proanthocyanidins). These aforementioned compounds are known for their anti-inflammatory effects. Pistachios also have been shown to reduce the risk of cardiovascular disease, metabolic syndrome, and all-cause mortality. The purpose of this study will be to determine the effects of consuming 1.5 ounces of pistachios per day compared to consuming no pistachios per day on inflammatory markers (creatine kinase, C-reactive protein, cortisol, Interleukin-8, tumor necrosis factor-alpha, copper-zinc superoxide dismutase, and glutathione peroxidase concentrations) and lean body mass in women and men, 40 to 60 years of age, who have been recreationally active for at least six months (exercising three to five days per week). It is hypothesized that pistachio consumption will significantly lower inflammatory response and significantly increase lean body mass. This will be a randomized study where participants will first complete a two-week baseline run-in period during which they will consume their typical diet. Following this, participants will be randomized to one of two groups for six months: consuming 1.5 ounces of pistachios per day or a control group (consuming no pistachios). Those consuming pistachios will be in addition to their usual diet. The overall goal of this study is to evaluate the effects of pistachio consumption on inflammatory markers and lean body mass in women an
Primary Outcome
C-reactive protein measures inflammation in the body
Conditions Studied
Interventions
- OTHER Pistachio group
Study Locations (1)
Virginia
- Virginia Polytechnic Institute and State University - Blacksburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 144 participants |
| Start Date | 2024-02-20 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
What the registry record for NCT06342024 still lists
NCT06342024 is an interventional study that assigns participants to a tested intervention. The registered 144 participants enrollment target is mid-sized for trials with a published cap, below the 169-participant average among 16 other Inflammatory Response trials with a reported enrollment target (15% lower).
The record links to 1 condition, with Inflammatory Response appearing as the primary indexed condition, and to 1 intervention - of which Pistachio group is the first listed.
NCT06342024 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT06342024 about?
NCT06342024 is a clinical study titled "Pistachio Consumption on Inflammatory Markers and Lean Body Mass". Pistachio nuts (Pistacia vera L.) are a nutrient- and energy-dense food, and are a significant source of 15 different micronutrients. In addition to an excellent micronutrient profile, pistachios are a good source of monounsaturated and polyunsaturated fats (linoleic acid, oleic acid, and plant ster...
What is the current status of trial NCT06342024?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 144 participants. The study started on 2024-02-20. Estimated completion is 2026-08-31.
What conditions does trial NCT06342024 study?
This clinical trial studies the following conditions: Inflammatory Response.
What interventions are being tested in trial NCT06342024?
The interventions under investigation include: Pistachio group (OTHER).
Who is sponsoring clinical trial NCT06342024?
This trial is sponsored by Virginia Polytechnic Institute and State University, which has 104 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06342024 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06342024's enrollment target sits among peer trials
144 4th of 16 higher than 13 of 16 other Inflammatory Response trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Inflammatory Response trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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