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NCT05934708 · ClinicalTrials.gov registry record · NA

Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise

A NA study of Inflammatory Response, sponsored by University of Southern California.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT05934708: Recruiting NA study of Inflammatory Response, sponsored by University of Southern California.

NCT05934708 is a NA study of Inflammatory Response that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 30 participants, below the 176-participant average among 16 other Inflammatory Response trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05934708, a NA study of Inflammatory Response, is actively recruiting participants, sponsored by University of Southern California.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The fluctuating concentrations of female sex hormones, namely estrogen and progesterone may have an effect on the ability of the tissue to withstand challenging exercise conditions, such as eccentric exercise. These sex hormones have also been purported to influence the perceived difficulty of exercise. This study aims to uncover how the different estrogen and progesterone concentrations present throughout the menstrual cycle effect perceived readiness to perform, perceptions of difficulty, and different recovery metrics.

Primary Outcome

Perceived readiness will be measured on an 11 point numeric rating scale (NRS) with 0 being not ready at all, and 10 being most prepared

Conditions Studied

Interventions

  • BEHAVIORAL Eccentric leg extension

Study Locations (1)

California

  • Clinical Exercise Research Center - Los Angeles

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-03-07
Est. Completion 2026-08
Phase NA
University of Southern California

617 total trials

What NCT05934708 shows while recruiting

NCT05934708 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 176-participant average among 16 other Inflammatory Response trials with a reported enrollment target (83% lower).

The record links to 1 condition, with Inflammatory Response appearing as the primary indexed condition, and to 1 intervention - of which Eccentric leg extension is the first listed.

NCT05934708 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05934708 about?

NCT05934708 is a clinical study titled "Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise". The fluctuating concentrations of female sex hormones, namely estrogen and progesterone may have an effect on the ability of the tissue to withstand challenging exercise conditions, such as eccentric exercise. These sex hormones have also been purported to influence the perceived difficulty of exerc...

What is the current status of trial NCT05934708?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-03-07. Estimated completion is 2026-08.

What conditions does trial NCT05934708 study?

This clinical trial studies the following conditions: Inflammatory Response.

What interventions are being tested in trial NCT05934708?

The interventions under investigation include: Eccentric leg extension (BEHAVIORAL).

Who is sponsoring clinical trial NCT05934708?

This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05934708 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Inflammatory Response

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05934708's enrollment target sits among peer trials

30 15th of 16 higher than 2 of 16 other Inflammatory Response trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Inflammatory Response trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05934708, the US trial registry maintained by the National Library of Medicine. NCT05934708 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.