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NCT06311123 · ClinicalTrials.gov registry record
Understanding Ozanimod's MOA Via Mass Cytometry in Ulcerative Colitis
A clinical trial of Ulcerative Colitis and Ulcerative Colitis Chronic Moderate, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- 10
- Enrollment target
- 1
- Study location
NCT06311123: Recruiting study of Ulcerative Colitis and Ulcerative Colitis Chronic Moderate, sponsored by University of California, San Diego.
NCT06311123 is a study of Ulcerative Colitis and Ulcerative Colitis Chronic Moderate that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 10 participants, below the 2,057-participant average among 122 other Ulcerative Colitis trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06311123, a study of Ulcerative Colitis and Ulcerative Colitis Chronic Moderate, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational study is to learn about the mechanism of action of ozanimod in patients with ulcerative colitis (UC). The main questions it aims to answer are: 1. Prospectively assess the effects of ozanimod on the cellular composition of intestinal lamina propria and blood by deep immunophenotyping (CyTOF) of immune cell subsets prior and after the drug's administration. 2. Determine whether changes in cell subsets observed via mass cytometry correlate with with clinical or histologic parameters of disease activity. Colonic biopsies and peripheral blood samples will be collected from patients with UC before and after the onset of ozanimod. Researchers will compare intestinal and peripheral leukocytes before and after the drug's administration.
Primary Outcome
difference in leukocyte subsets as determined by mass cytometry analyses
Conditions Studied
Study Locations (1)
California
- University of California San Diego - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2023-10-06 |
| Est. Completion | 2026-09-30 |
What NCT06311123 shows while recruiting
NCT06311123 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 2,057-participant average among 122 other Ulcerative Colitis trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Ulcerative Colitis appearing as the primary indexed condition, and to 0 interventions.
NCT06311123 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06311123 about?
NCT06311123 is a clinical study titled "Understanding Ozanimod's MOA Via Mass Cytometry in Ulcerative Colitis". The goal of this observational study is to learn about the mechanism of action of ozanimod in patients with ulcerative colitis (UC). The main questions it aims to answer are: 1. Prospectively assess the effects of ozanimod on the cellular composition of intestinal lamina propria and blood by deep i...
What is the current status of trial NCT06311123?
This trial is currently recruiting. The enrollment target is 10 participants. The study started on 2023-10-06. Estimated completion is 2026-09-30.
What conditions does trial NCT06311123 study?
This clinical trial studies the following conditions: Ulcerative Colitis, Ulcerative Colitis Chronic Moderate.
Who is sponsoring clinical trial NCT06311123?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06311123 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06311123's enrollment target sits among peer trials
10 121st of 122 higher than 1 of 122 other Ulcerative Colitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ulcerative Colitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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