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NCT06293794 · ClinicalTrials.gov registry record · NA
Decision Support for Heart Failure Prescribing
A NA study of Heart Failure and Decision Support Systems, Clinical, sponsored by University of Colorado, Denver.
- Active
- Registry status
- NA
- Development phase
- 764
- Enrollment target
- 1
- Study location
NCT06293794: Active NA study of Heart Failure and Decision Support Systems, Clinical, sponsored by University of Colorado, Denver.
NCT06293794 is a NA study of Heart Failure and Decision Support Systems, Clinical that is active but no longer recruiting, run by University of Colorado, Denver. The registered enrollment target is 764 participants, below the 2,047-participant average among 397 other Heart Failure trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06293794, a NA study of Heart Failure and Decision Support Systems, Clinical, is active but no longer recruiting, sponsored by University of Colorado, Denver.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 764 participants
- Enrollment target
- 1
- Study location
Study Summary
Clinical decision support (CDS) tools can 'nudge' clinicians to make the best decisions easy. Although required by "meaningful use" regulations, more than 40% of CDS lead to no change and the remaining lead to improvements that are modest at best. This is because CDS tools often ignore contextual factors and present irrelevant information. Although many tools have undergone patient-specific optimization, 'traditional CDS' are rarely clinician-specific. For example, a traditional CDS tool for beta blockers and heart failure with reduced ejection fraction (HFrEF) addresses common prescribing misconceptions by stating asthma is not a contraindication and providing a safe threshold for blood pressure. For clinicians without these misconceptions, these statements are irrelevant and distract from key information. A 'personalized CDS' would evaluate clinician past prescribing patterns to determine whether prescribing misconceptions might exist and then conditionally present information to address those misconceptions. The objective of this research is to create personalized clinician-specific CDS that overcome shortcomings of traditional CDS. The central hypothesis is a personalized CDS that minimizes irrelevant information will lead to a higher rate of prescribing guideline-directed management and therapy (GDMT) for HFrEF compared to a traditional CDS.
Primary Outcome
The primary outcome is number of CDS alerts that resulted in the prescription of the medication recommended by the CDS alert. Recommended medications include either evidence-based beta blockers, sacubitril/valsartan, mineralocorticoid receptor antagonists or sodium/glucose cotransport 2 inhibitors. Prescriptions will be based on actual prescription orders instead of clinician-stated responses, given the latter may overestimate effectiveness.
Conditions Studied
Interventions
- OTHER Personalized Clinical Decision Support (CDS)
- OTHER Traditional Clinical Decision Support (CDS)
Study Locations (1)
Colorado
- UCHealth Primary Care and Cardiology Outpatient Clinics - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 764 participants |
| Start Date | 2025-02-11 |
| Est. Completion | 2025-09 |
| Phase | NA |
What the registry record for NCT06293794 still lists
NCT06293794 is an interventional study that assigns participants to a tested intervention. The registered 764 participants enrollment target is mid-sized for trials with a published cap, below the 2,047-participant average among 397 other Heart Failure trials with a reported enrollment target (63% lower).
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Personalized Clinical Decision Support (CDS) is the first listed.
NCT06293794 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT06293794 about?
NCT06293794 is a clinical study titled "Decision Support for Heart Failure Prescribing". Clinical decision support (CDS) tools can 'nudge' clinicians to make the best decisions easy. Although required by "meaningful use" regulations, more than 40% of CDS lead to no change and the remaining lead to improvements that are modest at best. This is because CDS tools often ignore contextual fa...
What is the current status of trial NCT06293794?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 764 participants. The study started on 2025-02-11. Estimated completion is 2025-09.
What conditions does trial NCT06293794 study?
This clinical trial studies the following conditions: Heart Failure, Decision Support Systems, Clinical.
What interventions are being tested in trial NCT06293794?
The interventions under investigation include: Personalized Clinical Decision Support (CDS) (OTHER), Traditional Clinical Decision Support (CDS) (OTHER).
Who is sponsoring clinical trial NCT06293794?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06293794 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06293794's enrollment target sits among peer trials
764 82nd of 397 higher than 316 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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