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NCT06293040 · ClinicalTrials.gov registry record · Phase 1

Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment

A Phase 1 study of Alcohol Intoxication and Cannabis Intoxication, sponsored by Johns Hopkins University.

Recruiting
Registry status
Phase 1
Development phase
90
Enrollment target
1
Study location

NCT06293040: Recruiting Phase 1 study of Alcohol Intoxication and Cannabis Intoxication, sponsored by Johns Hopkins University.

NCT06293040 is a Phase 1 study of Alcohol Intoxication and Cannabis Intoxication that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 90 participants, below the 342-participant average among 15 other Alcohol Intoxication trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06293040, a Phase 1 study of Alcohol Intoxication and Cannabis Intoxication, is actively recruiting participants, sponsored by Johns Hopkins University.

RECRUITING
Registry status
Phase 1
Development phase
90 participants
Enrollment target
1
Study location

Study Summary

This human laboratory study will use cognitive, behavioral, and subjective measures to characterize impairment associated with co-use of alcohol and vaporized cannabis. Participants (n=32) will complete 7 double-blind, double-dummy outpatient sessions in randomized order. In each session, participants will self-administer placebo (0 mg THC) or active vaporized cannabis (5 or 25 mg THC, via a handheld vaporizer called the Mighty Medic) and a placebo drink (BAC 0.0%) or alcohol drink calculated to produce a breath alcohol concentration (BAC) of 0.05%. Participants will also complete a positive control session in which the participant administers placebo cannabis and alcohol at a target BAC of 0.08% (the legal threshold for driving impairment in most U.S. states).

Primary Outcome

Acute cognitive and behavioral impairment will be assessed with global impairment score (range 0-100) on the DRUID app (higher scores indicate greater impairment).

Conditions Studied

Alcohol Intoxication Cannabis Intoxication

Interventions

  • DRUG Alcohol
  • DRUG Cannabis
  • DRUG Placebo Cannabis
  • DRUG Placebo Alcohol

Study Locations (1)

Maryland

  • Johns Hopkins Behavioral Pharmacology Research Unit - Baltimore

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2024-09-26
Est. Completion 2027-12
Phase Phase 1
Johns Hopkins University

1,448 total trials

What NCT06293040 shows while recruiting

NCT06293040 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 342-participant average among 15 other Alcohol Intoxication trials with a reported enrollment target (74% lower).

The record links to 2 conditions, with Alcohol Intoxication appearing as the primary indexed condition, and to 4 interventions - of which Alcohol is the first listed.

NCT06293040 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT06293040 about?

NCT06293040 is a clinical study titled "Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment". This human laboratory study will use cognitive, behavioral, and subjective measures to characterize impairment associated with co-use of alcohol and vaporized cannabis. Participants (n=32) will complete 7 double-blind, double-dummy outpatient sessions in randomized order. In each session, participan...

What is the current status of trial NCT06293040?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 90 participants. The study started on 2024-09-26. Estimated completion is 2027-12.

What conditions does trial NCT06293040 study?

This clinical trial studies the following conditions: Alcohol Intoxication, Cannabis Intoxication.

What interventions are being tested in trial NCT06293040?

The interventions under investigation include: Alcohol (DRUG), Cannabis (DRUG), Placebo Cannabis (DRUG), Placebo Alcohol (DRUG).

Who is sponsoring clinical trial NCT06293040?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06293040 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Alcohol Intoxication

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06293040's enrollment target sits among peer trials

90 13th of 15 higher than 3 of 15 other Alcohol Intoxication trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Alcohol Intoxication trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT06293040

Source: ClinicalTrials.gov NCT06293040, the US trial registry maintained by the National Library of Medicine. NCT06293040 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.