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NCT06285474 · ClinicalTrials.gov registry record · NA
Investigating LIFUP in Anhedonic Depression
A NA study of Depression and Anhedonia, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 56
- Enrollment target
- 1
- Study location
NCT06285474: Completed NA study of Depression and Anhedonia, sponsored by University of California, Los Angeles.
NCT06285474 is a NA study of Depression and Anhedonia that has completed, run by University of California, Los Angeles. The registered enrollment target is 56 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06285474, a NA study of Depression and Anhedonia, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will observe changes in brain imaging, behavior, and symptom measures following intervention with low intensity focused ultrasound pulsation (LIFUP) targeting reward circuitry in individuals who are depressed and anhedonic.
Primary Outcome
Validated, self-report, 14 item assessment of depressive symptoms in the past 2 weeks. Score range 0- 24. Higher scores indicate higher severity of depressive symptoms.
Conditions Studied
Interventions
- DEVICE Low Intensity Focused Ultrasound Pulsation (LIFUP)
Study Locations (1)
California
- University of California Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2022-10-27 |
| Est. Completion | 2024-04-24 |
| Phase | NA |
What the finished NCT06285474 record still lists
NCT06285474 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Low Intensity Focused Ultrasound Pulsation (LIFUP) is the first listed.
NCT06285474 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06285474 about?
NCT06285474 is a clinical study titled "Investigating LIFUP in Anhedonic Depression". This study will observe changes in brain imaging, behavior, and symptom measures following intervention with low intensity focused ultrasound pulsation (LIFUP) targeting reward circuitry in individuals who are depressed and anhedonic.
What is the current status of trial NCT06285474?
This trial is currently completed. It is a NA study. The enrollment target is 56 participants. The study started on 2022-10-27. Estimated completion is 2024-04-24.
What conditions does trial NCT06285474 study?
This clinical trial studies the following conditions: Depression, Anhedonia.
What interventions are being tested in trial NCT06285474?
The interventions under investigation include: Low Intensity Focused Ultrasound Pulsation (LIFUP) (DEVICE).
Who is sponsoring clinical trial NCT06285474?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06285474 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06285474's enrollment target sits among peer trials
56 454th of 679 higher than 225 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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