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ACTIVE NOT RECRUITING Phase 3

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)

NCT06270836 · View on ClinicalTrials.gov ↗

Study Summary

This study will demonstrate that tarcocimab 5 mg is superior to sham treatment in participants with DR.

Conditions Studied

Interventions

  • OTHER Sham injection
  • DRUG Tarcocimab

Study Locations (20)

California

  • Retina Consultants of Orange County — Fullerton
  • Global Research Management, Inc. - Lugene Eye Institute — Glendale
  • Retinal Consultants Medical Group, Inc. — Modesto
  • Retina Consultants of Southern California — Redlands
  • Retinal Consultants Medical Group, Inc. — Sacramento

North Carolina

  • Asheville Eye Associates — Asheville
  • North Carolina Retina Associates (Cary) — Cary
  • North Carolina Retina Associates (Wake Forest) — Wake Forest

Florida

  • Retina Group of Florida — Fort Lauderdale
  • Center for Retina and Macular Disease — Winter Haven

Arizona

  • Retina Associates SW — Tucson

Connecticut

  • Retina Group of New England, PC — Waterford

Georgia

  • Southeast Retina Center — Augusta

Illinois

  • Springfield Clinic LLP — Springfield

Indiana

  • Associated Vitreoretinal and Uveitis Consultants — Carmel

Trial Details

FieldValue
Enrollment Target 255 participants
Start Date 2024-05-01
Est. Completion 2026-01-31
Phase Phase 3

Sponsor

Kodiak Sciences

5 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06270836

The ClinicalTrials.gov registry entry for NCT06270836 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 255 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Kodiak Sciences, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Diabetic Retinopathy appearing as the primary indexed condition, and to 2 interventions — of which Sham injection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06270836 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, North Carolina, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06270836 about?

NCT06270836 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)". This study will demonstrate that tarcocimab 5 mg is superior to sham treatment in participants with DR.

What is the current status of trial NCT06270836?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 255 participants. The study started on 2024-05-01. Estimated completion is 2026-01-31.

What conditions does trial NCT06270836 study?

This clinical trial studies the following conditions: Diabetic Retinopathy. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06270836?

The interventions under investigation include: Sham injection (OTHER), Tarcocimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06270836?

This trial is sponsored by Kodiak Sciences, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06270836 being conducted?

This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial