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NCT06268431 · ClinicalTrials.gov registry record · NA
Oxytocin Rest to Reduce Cesarean Delivery
A NA study of Labor Dystocia and Prolonged Labor, sponsored by Christiana Care Health Services.
- Recruiting
- Registry status
- NA
- Development phase
- 350
- Enrollment target
- 1
- Study location
NCT06268431: Recruiting NA study of Labor Dystocia and Prolonged Labor, sponsored by Christiana Care Health Services.
NCT06268431 is a NA study of Labor Dystocia and Prolonged Labor that is actively recruiting participants, run by Christiana Care Health Services. The registered enrollment target is 350 participants, above the 116-participant average among 3 other Labor Dystocia trials with a reported enrollment target (202% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06268431, a NA study of Labor Dystocia and Prolonged Labor, is actively recruiting participants, sponsored by Christiana Care Health Services.
- RECRUITING
- Registry status
- NA
- Development phase
- 350 participants
- Enrollment target
- 1
- Study location
Study Summary
Prolonged labor is usually managed with continuous oxytocin infusion. "Oxytocin rest" has been proposed as a strategy to resolve protracted labor in patients who have received continuous oxytocin without progress. This strategy involves discontinuing oxytocin then restarting infusion after a period of time, under the theory that washout of the oxytocin receptor will strengthen uterine contractions to improve labor progress. "Oxytocin rest" is performed on labor and delivery units across the United States. Yet, there is no randomized or prospective data to support the practice. The purpose of this study is to assess whether oxytocin rest of 60 minutes in patients with prolonged labor reduces risk for cesarean delivery.
Primary Outcome
Number of participants delivered by cesarean
Conditions Studied
Interventions
- OTHER Oxytocin rest
Study Locations (1)
Delaware
- ChristianaCare Health System - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 350 participants |
| Start Date | 2024-03-19 |
| Est. Completion | 2026-03-15 |
| Phase | NA |
What NCT06268431 shows while recruiting
NCT06268431 is an interventional study that assigns participants to a tested intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, above the 116-participant average among 3 other Labor Dystocia trials with a reported enrollment target (202% higher).
The record links to 3 conditions, with Labor Dystocia appearing as the primary indexed condition, and to 1 intervention - of which Oxytocin rest is the first listed.
NCT06268431 reports a single indexed study location in Delaware.
Frequently Asked Questions
What is clinical trial NCT06268431 about?
NCT06268431 is a clinical study titled "Oxytocin Rest to Reduce Cesarean Delivery". Prolonged labor is usually managed with continuous oxytocin infusion. "Oxytocin rest" has been proposed as a strategy to resolve protracted labor in patients who have received continuous oxytocin without progress. This strategy involves discontinuing oxytocin then restarting infusion after a period ...
What is the current status of trial NCT06268431?
This trial is currently recruiting. It is a NA study. The enrollment target is 350 participants. The study started on 2024-03-19. Estimated completion is 2026-03-15.
What conditions does trial NCT06268431 study?
This clinical trial studies the following conditions: Labor Dystocia, Prolonged Labor, Failed Induction.
What interventions are being tested in trial NCT06268431?
The interventions under investigation include: Oxytocin rest (OTHER).
Who is sponsoring clinical trial NCT06268431?
This trial is sponsored by Christiana Care Health Services, which has 82 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06268431 being conducted?
This trial has 1 study location across Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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