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NCT06265532 · ClinicalTrials.gov registry record · Phase 1
Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect
A Phase 1 study of Idiopathic Pulmonary Fibrosis, sponsored by Hal Chapman.
- Active
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
- 3
- Study locations
NCT06265532: Active Phase 1 study of Idiopathic Pulmonary Fibrosis, sponsored by Hal Chapman.
NCT06265532 is a Phase 1 study of Idiopathic Pulmonary Fibrosis that is active but no longer recruiting, run by Hal Chapman. The registered enrollment target is 22 participants, below the 751-participant average among 51 other Idiopathic Pulmonary Fibrosis trials with a reported enrollment target (97% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06265532, a Phase 1 study of Idiopathic Pulmonary Fibrosis, is active but no longer recruiting, sponsored by Hal Chapman.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
- 3
- Study locations
Study Summary
The primary purpose of this substudy is to determine if collagen-targeted PET using the type 1 collagen-targeted PET probe, Gallium-68 (68Ga)-labeled collagen binding probe 8 (CBP8) can inform as to drug effect of EGCG and assist in dose selection.
Primary Outcome
Changes in lung collagen uptake will be measured using the PET probe \[68\]Ga-CBP8. Measurements will be made over the entire lungs using standardized uptake values.
Conditions Studied
Interventions
- DRUG EGCG 300 mg
- DRUG Placebo for EGCG 300 mg
- DRUG EGCG 600 mg
- DRUG Placebo for EGCG 600 mg
Study Locations (3)
Massachusetts
- Massachusetts General Hospital - Boston
Michigan
- University of Michigan - Ann Arbor
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2024-02-07 |
| Est. Completion | 2026-03-25 |
| Phase | Phase 1 |
What the registry record for NCT06265532 still lists
NCT06265532 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 751-participant average among 51 other Idiopathic Pulmonary Fibrosis trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Idiopathic Pulmonary Fibrosis appearing as the primary indexed condition, and to 4 interventions - of which EGCG 300 mg is the first listed.
NCT06265532 reports a single indexed study location in Massachusetts, Michigan, Virginia.
Frequently Asked Questions
What is clinical trial NCT06265532 about?
NCT06265532 is a clinical study titled "Collagen-targeted Positron Emission Tomography (PET) Imaging for Assessment of EGCG Effect". The primary purpose of this substudy is to determine if collagen-targeted PET using the type 1 collagen-targeted PET probe, Gallium-68 (68Ga)-labeled collagen binding probe 8 (CBP8) can inform as to drug effect of EGCG and assist in dose selection.
What is the current status of trial NCT06265532?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2024-02-07. Estimated completion is 2026-03-25.
What conditions does trial NCT06265532 study?
This clinical trial studies the following conditions: Idiopathic Pulmonary Fibrosis.
What interventions are being tested in trial NCT06265532?
The interventions under investigation include: EGCG 300 mg (DRUG), Placebo for EGCG 300 mg (DRUG), EGCG 600 mg (DRUG), Placebo for EGCG 600 mg (DRUG).
Who is sponsoring clinical trial NCT06265532?
This trial is sponsored by Hal Chapman, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06265532 being conducted?
This trial has 3 study locations across Massachusetts, Michigan, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Idiopathic Pulmonary Fibrosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06265532's enrollment target sits among peer trials
22 42nd of 51 higher than 10 of 51 other Idiopathic Pulmonary Fibrosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Idiopathic Pulmonary Fibrosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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