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NCT06253585 · ClinicalTrials.gov registry record · NA
Precision Resuscitation With Crystalloids in Sepsis
A NA study, sponsored by Emory University.
- Completed
- Registry status
- NA
- Development phase
- 2,012
- Enrollment target
NCT06253585: Completed NA study, sponsored by Emory University.
NCT06253585 is a NA study that has completed, run by Emory University. The registered enrollment target is 2,012 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (43% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06253585, a NA study, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,012 participants
- Enrollment target
Study Summary
Fluids are one of the most common treatments given to patients in the hospital. Fluids are especially important in treating patients with sepsis. Multiple clinical studies have compared the two main types of fluids used in sepsis (normal saline and balanced crystalloids). However, these studies have not found a clear benefit of one type of fluid versus the other. Which fluid should be given to which patient is an essential question because of the ubiquity of this intervention. Even a small difference in mortality could drastically change the standards of care given the national (and worldwide) scale of this intervention. The investigators have developed an algorithm that uses bedside vital signs (temperature, heart rate, respiratory rate, and blood pressure) to identify a group of patients (Group D) who have a significant mortality benefit from balanced crystalloids. The study randomizes adult patients admitted through emergency departments across 6 Emory hospitals belonging to Group D to intervention versus usual care. The intervention arm involves a prompt to clinicians to use balanced crystalloids rather than normal saline.
Primary Outcome
Thirty-day mortality
Interventions
- OTHER Standard of Care
- OTHER Algorithm Alarm- Crystalloids
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,012 participants |
| Start Date | 2024-06-13 |
| Est. Completion | 2025-12-19 |
| Phase | NA |
What the finished NCT06253585 record still lists
NCT06253585 is an interventional study that assigns participants to a tested intervention. Its 2,012 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (43% higher).
The record links to 0 conditions, and to 2 interventions - of which Standard of Care is the first listed.
NCT06253585 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06253585 about?
NCT06253585 is a clinical study titled "Precision Resuscitation With Crystalloids in Sepsis". Fluids are one of the most common treatments given to patients in the hospital. Fluids are especially important in treating patients with sepsis. Multiple clinical studies have compared the two main types of fluids used in sepsis (normal saline and balanced crystalloids). However, these studies have...
What is the current status of trial NCT06253585?
This trial is currently completed. It is a NA study. The enrollment target is 2,012 participants. The study started on 2024-06-13. Estimated completion is 2025-12-19.
What interventions are being tested in trial NCT06253585?
The interventions under investigation include: Standard of Care (OTHER), Algorithm Alarm- Crystalloids (OTHER).
Who is sponsoring clinical trial NCT06253585?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06253585's enrollment target sits among peer trials
2,012 52nd of 2000 higher than 1,949 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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