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NCT06245915 · ClinicalTrials.gov registry record · Phase 1

AB-2100, an Integrated Circuit T Cell Therapy in Patients With Recurrent Clear-cell Renal Cell Carcinoma (ccRCC)

A Phase 1 study of Recurrence and Advanced/Metastatic Clear Cell Renal Cell Carcinoma, sponsored by Arsenal Biosciences.

Active
Registry status
Phase 1
Development phase
37
Enrollment target
9
Study locations

NCT06245915 is a Phase 1 study of Recurrence and Advanced/Metastatic Clear Cell Renal Cell Carcinoma that is active but no longer recruiting, run by Arsenal Biosciences. The registered enrollment target is 37 participants, below the 529-participant average among 8 other Recurrence trials with a reported enrollment target (93% lower). The trial reports 9 study locations across 8 states.

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The verdict

NCT06245915, a Phase 1 study of Recurrence and Advanced/Metastatic Clear Cell Renal Cell Carcinoma, is active but no longer recruiting, sponsored by Arsenal Biosciences.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
37 participants
Enrollment target
9
Study locations

Study Summary

This is a multi-center, open-label phase 1/2 trial evaluating the safety and efficacy of AB-2100 cell product. The study may enroll approximately 60 patients in phase 1 and approximately 70 patients in phase 2.

Interventions

  • BIOLOGICAL AB-2100

Study Locations (9)

New York

  • Perlmutter Cancer Center - NYU Langone Health - New York
  • Memorial Sloan Kettering Cancer Center - New York

Arizona

  • Mayo Clinic Hospital - Phoenix

California

  • City of Hope - Duarte

Florida

  • Moffitt Cancer Center - Tampa

Iowa

  • University of Iowa and Holden Comprehensive Cancer Center - Iowa City

Massachusetts

  • Dana Farber Cancer Institue - Boston

Texas

  • MD Anderson Cancer Center - Houston

Utah

  • Huntsman Cancer Institute - Univ of Utah Health - Salt Lake City

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2024-02-26
Est. Completion 2028-06-30
Phase Phase 1

Sponsor

Arsenal Biosciences

3 total trials

What the Registry Record Tells You About NCT06245915

The ClinicalTrials.gov registry entry for NCT06245915 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 529-participant average among 8 other Recurrence trials with a reported enrollment target (93% lower). The listed sponsor is Arsenal Biosciences, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Recurrence appearing as the primary indexed condition, and to 1 intervention - of which AB-2100 is the first listed.

NCT06245915 reports 9 study locations spanning 8 distinct geographic areas - top geographies include New York, Arizona, California.

Frequently Asked Questions

What is clinical trial NCT06245915 about?

NCT06245915 is a clinical study titled "AB-2100, an Integrated Circuit T Cell Therapy in Patients With Recurrent Clear-cell Renal Cell Carcinoma (ccRCC)". This is a multi-center, open-label phase 1/2 trial evaluating the safety and efficacy of AB-2100 cell product. The study may enroll approximately 60 patients in phase 1 and approximately 70 patients in phase 2.

What is the current status of trial NCT06245915?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2024-02-26. Estimated completion is 2028-06-30.

What conditions does trial NCT06245915 study?

This clinical trial studies the following conditions: Recurrence, Advanced/Metastatic Clear Cell Renal Cell Carcinoma.

What interventions are being tested in trial NCT06245915?

The interventions under investigation include: AB-2100 (BIOLOGICAL).

Who is sponsoring clinical trial NCT06245915?

This trial is sponsored by Arsenal Biosciences, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06245915 being conducted?

This trial has 9 study locations across Arizona, California, Florida, Iowa, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.