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ACTIVE NOT RECRUITING Phase 1

AB-2100, an Integrated Circuit T Cell Therapy in Patients With Recurrent Clear-cell Renal Cell Carcinoma (ccRCC)

NCT06245915 · View on ClinicalTrials.gov ↗

Study Summary

This is a multi-center, open-label phase 1/2 trial evaluating the safety and efficacy of AB-2100 cell product. The study may enroll approximately 60 patients in phase 1 and approximately 70 patients in phase 2.

Interventions

  • BIOLOGICAL AB-2100

Study Locations (9)

New York

  • Perlmutter Cancer Center - NYU Langone Health — New York
  • Memorial Sloan Kettering Cancer Center — New York

Arizona

  • Mayo Clinic Hospital — Phoenix

California

  • City of Hope — Duarte

Florida

  • Moffitt Cancer Center — Tampa

Iowa

  • University of Iowa and Holden Comprehensive Cancer Center — Iowa City

Massachusetts

  • Dana Farber Cancer Institue — Boston

Texas

  • MD Anderson Cancer Center — Houston

Utah

  • Huntsman Cancer Institute - Univ of Utah Health — Salt Lake City

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2024-02-26
Est. Completion 2028-06-30
Phase Phase 1

Sponsor

Arsenal Biosciences

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06245915

The ClinicalTrials.gov registry entry for NCT06245915 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Arsenal Biosciences, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Recurrence appearing as the primary indexed condition, and to 1 intervention — of which AB-2100 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06245915 reports 9 study locations spanning 8 distinct geographic areas — top geographies include New York, Arizona, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06245915 about?

NCT06245915 is a clinical study titled "AB-2100, an Integrated Circuit T Cell Therapy in Patients With Recurrent Clear-cell Renal Cell Carcinoma (ccRCC)". This is a multi-center, open-label phase 1/2 trial evaluating the safety and efficacy of AB-2100 cell product. The study may enroll approximately 60 patients in phase 1 and approximately 70 patients in phase 2.

What is the current status of trial NCT06245915?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2024-02-26. Estimated completion is 2028-06-30.

What conditions does trial NCT06245915 study?

This clinical trial studies the following conditions: Recurrence, Advanced/Metastatic Clear Cell Renal Cell Carcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06245915?

The interventions under investigation include: AB-2100 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06245915?

This trial is sponsored by Arsenal Biosciences, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06245915 being conducted?

This trial has 9 study locations across Arizona, California, Florida, Iowa, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial