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NCT03865537 · ClinicalTrials.gov registry record · NA
Cold Snare Endoscopic Mucosal Resection Trial
A NA study of Colonoscopy and Recurrence, sponsored by White River Junction Veterans Affairs Medical Center.
- Active
- Registry status
- NA
- Development phase
- 990
- Enrollment target
- 1
- Study location
NCT03865537: Active NA study of Colonoscopy and Recurrence, sponsored by White River Junction Veterans Affairs Medical Center.
NCT03865537 is a NA study of Colonoscopy and Recurrence that is active but no longer recruiting, run by White River Junction Veterans Affairs Medical Center. The registered enrollment target is 990 participants, above the 452-participant average among 20 other Colonoscopy trials with a reported enrollment target (119% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03865537, a NA study of Colonoscopy and Recurrence, is active but no longer recruiting, sponsored by White River Junction Veterans Affairs Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 990 participants
- Enrollment target
- 1
- Study location
Study Summary
This study compares different approaches to endoscopic mucosal resection (EMR) of large non-pedunculated colorectal polyps (≥20mm) in a 2 x 2 randomized design. The first randomization will assign half of patients to polyp resection with electrocautery ("hot" snare EMR) and half of patient to polyp resection without electrocautery ("cold" snare EMR). The second randomization will assign half of patients to polyp removal using Eleview as the submucosal injection agent, and the other half using placebo (normal saline with methylene blue) as the submucosal injection agent.
Primary Outcome
Aggregate of all severe adverse events that occur at the time of the colonoscopy with resection of the large polyp or following the procedure
Conditions Studied
Interventions
- PROCEDURE Cold snare EMR
- PROCEDURE Hot snare EMR
- PROCEDURE Eleview injection
- PROCEDURE Placebo injection
Study Locations (1)
Vermont
- White River Junction VAMC - White River Junction
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 990 participants |
| Start Date | 2019-10-01 |
| Est. Completion | 2027-01 |
| Phase | NA |
What the registry record for NCT03865537 still lists
NCT03865537 is an interventional study that assigns participants to a tested intervention. The registered 990 participants enrollment target is mid-sized for trials with a published cap, above the 452-participant average among 20 other Colonoscopy trials with a reported enrollment target (119% higher).
The record links to 4 conditions, with Colonoscopy appearing as the primary indexed condition, and to 4 interventions - of which Cold snare EMR is the first listed.
NCT03865537 reports a single indexed study location in Vermont.
Frequently Asked Questions
What is clinical trial NCT03865537 about?
NCT03865537 is a clinical study titled "Cold Snare Endoscopic Mucosal Resection Trial". This study compares different approaches to endoscopic mucosal resection (EMR) of large non-pedunculated colorectal polyps (≥20mm) in a 2 x 2 randomized design. The first randomization will assign half of patients to polyp resection with electrocautery ("hot" snare EMR) and half of patient to polyp ...
What is the current status of trial NCT03865537?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 990 participants. The study started on 2019-10-01. Estimated completion is 2027-01.
What conditions does trial NCT03865537 study?
This clinical trial studies the following conditions: Colonoscopy, Recurrence, Complication, Colonic Polyp.
What interventions are being tested in trial NCT03865537?
The interventions under investigation include: Cold snare EMR (PROCEDURE), Hot snare EMR (PROCEDURE), Eleview injection (PROCEDURE), Placebo injection (PROCEDURE).
Who is sponsoring clinical trial NCT03865537?
This trial is sponsored by White River Junction Veterans Affairs Medical Center, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03865537 being conducted?
This trial has 1 study location across Vermont. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colonoscopy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03865537's enrollment target sits among peer trials
990 3rd of 20 higher than 18 of 20 other Colonoscopy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colonoscopy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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