Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06234098 · ClinicalTrials.gov registry record · Phase 1
Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors
A Phase 1 study of Solid Tumor, sponsored by Alyssum Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 85
- Enrollment target
- 7
- Study locations
NCT06234098 is a Phase 1 study of Solid Tumor that is actively recruiting participants, run by Alyssum Therapeutics. The registered enrollment target is 85 participants, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (62% lower). The trial reports 7 study locations across 4 states.
The verdict
NCT06234098, a Phase 1 study of Solid Tumor, is actively recruiting participants, sponsored by Alyssum Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 85 participants
- Enrollment target
- 7
- Study locations
Study Summary
This is a first-in-human, multicenter, open-label, dose escalation and dose expansion Phase 1/2 study to determine the MTD and/or the recommended Phase 2 dose (RP2D) and to characterize DLTs of AT-1965 as well as to investigate the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of AT-1965 in patients with advanced, refractory or recurrent solid tumors (nonresectable and/or metastatic) including mTNBC.
Conditions Studied
Interventions
- DRUG AT-1965 Liposome Injection
Study Locations (7)
California
- CBCC Global Research Site 005 - Bakersfield
- CBCC Global Research Site 007 - El Segundo
- CBCC Global Research Site 008 - Santa Monica
- CBCC Global Research Site 003 - Stanford
Arizona
- CBCC Global Research Site 001 - Scottsdale
Oregon
- CBCC Global Research Site 002 - Portland
Texas
- CBCC Global Research Site 006 - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 85 participants |
| Start Date | 2024-02-13 |
| Est. Completion | 2027-01 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06234098
The ClinicalTrials.gov registry entry for NCT06234098 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 85 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 221-participant average among 196 other Solid Tumor trials with a reported enrollment target (62% lower). The listed sponsor is Alyssum Therapeutics, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which AT-1965 Liposome Injection is the first listed.
NCT06234098 reports 7 study locations spanning 4 distinct geographic areas - top geographies include California, Arizona, Oregon.
Frequently Asked Questions
What is clinical trial NCT06234098 about?
NCT06234098 is a clinical study titled "Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors". This is a first-in-human, multicenter, open-label, dose escalation and dose expansion Phase 1/2 study to determine the MTD and/or the recommended Phase 2 dose (RP2D) and to characterize DLTs of AT-1965 as well as to investigate the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary ant...
What is the current status of trial NCT06234098?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 85 participants. The study started on 2024-02-13. Estimated completion is 2027-01.
What conditions does trial NCT06234098 study?
This clinical trial studies the following conditions: Solid Tumor.
What interventions are being tested in trial NCT06234098?
The interventions under investigation include: AT-1965 Liposome Injection (DRUG).
Who is sponsoring clinical trial NCT06234098?
This trial is sponsored by Alyssum Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06234098 being conducted?
This trial has 7 study locations across Arizona, California, Oregon, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Solid Tumor
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors
RECRUITING · Phase 1
-
A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors
RECRUITING · Phase 1
-
Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors
RECRUITING · Phase 1
-
Concurrent Azeliragon With Craniospinal Irradiation
RECRUITING · Phase 1
-
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
RECRUITING · Phase 1
-
A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors
RECRUITING · Phase 1
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.