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NCT03875638 · ClinicalTrials.gov registry record · Phase 2

Treating Hyperexcitability in AD With Levetiracetam

A Phase 2 study of Alzheimer Disease and Mild Cognitive Impairment, sponsored by Beth Israel Deaconess Medical Center.

Recruiting
Registry status
Phase 2
Development phase
85
Enrollment target
1
Study location

NCT03875638 is a Phase 2 study of Alzheimer Disease and Mild Cognitive Impairment that is actively recruiting participants, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 85 participants, below the 2,750-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03875638, a Phase 2 study of Alzheimer Disease and Mild Cognitive Impairment, is actively recruiting participants, sponsored by Beth Israel Deaconess Medical Center.

RECRUITING
Registry status
Phase 2
Development phase
85 participants
Enrollment target
1
Study location

Study Summary

The aim of this study is to explore the relationship between cortical hyperexcitability, abnormalities of brain network function, and cognitive dysfunction in human patients with AD and whether administration of the antiepileptic medication levetiracetam (LEV) normalizes these measures and improves cognition.

Interventions

  • DRUG Levetiracetam
  • DRUG Placebo oral capsule

Study Locations (1)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 85 participants
Start Date 2019-08-22
Est. Completion 2025-11-30
Phase Phase 2

What the Registry Record Tells You About NCT03875638

The ClinicalTrials.gov registry entry for NCT03875638 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 85 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,750-participant average among 306 other Alzheimer Disease trials with a reported enrollment target (97% lower). The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Alzheimer Disease appearing as the primary indexed condition, and to 2 interventions - of which Levetiracetam is the first listed.

NCT03875638 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT03875638 about?

NCT03875638 is a clinical study titled "Treating Hyperexcitability in AD With Levetiracetam". The aim of this study is to explore the relationship between cortical hyperexcitability, abnormalities of brain network function, and cognitive dysfunction in human patients with AD and whether administration of the antiepileptic medication levetiracetam (LEV) normalizes these measures and improves ...

What is the current status of trial NCT03875638?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 85 participants. The study started on 2019-08-22. Estimated completion is 2025-11-30.

What conditions does trial NCT03875638 study?

This clinical trial studies the following conditions: Alzheimer Disease, Mild Cognitive Impairment, Dementia of Alzheimer Type, Alzheimer Dementia.

What interventions are being tested in trial NCT03875638?

The interventions under investigation include: Levetiracetam (DRUG), Placebo oral capsule (DRUG).

Who is sponsoring clinical trial NCT03875638?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03875638 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.