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NCT06227377 · ClinicalTrials.gov registry record · Phase 1

QTX3034 in Patients With KRAS G12D Mutation

A Phase 1 study of Solid Tumors, sponsored by Quanta Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
250
Enrollment target
14
Study locations

NCT06227377 is a Phase 1 study of Solid Tumors that is actively recruiting participants, run by Quanta Therapeutics. The registered enrollment target is 250 participants, below the 283-participant average among 125 other Solid Tumors trials with a reported enrollment target (12% lower). The trial reports 14 study locations across 11 states.

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The verdict

NCT06227377, a Phase 1 study of Solid Tumors, is actively recruiting participants, sponsored by Quanta Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
250 participants
Enrollment target
14
Study locations

Study Summary

Phase 1 study to determine the safety and tolerability of QTX3034 as a single agent or in combination with cetuximab.

Conditions Studied

Interventions

  • COMBINATION_PRODUCT Cetuximab
  • DRUG QTX3034

Study Locations (14)

Florida

  • Florida Cancer Specialists - Sarasota
  • Moffitt Cancer Center - Tampa

New York

  • NYU Langone Health - New York
  • Montefiore Medical Center - The Bronx

Texas

  • MD Anderson - Houston
  • START San Antonio, LLC - San Antonio

California

  • UCLA Hematology/Oncology - Los Angeles

Colorado

  • Sarah Cannon Research Institute (SCRI) - Denver

Connecticut

  • Yale Cancer Center - New Haven

North Carolina

  • Duke University - Durham

Oklahoma

  • Stephenson Cancer Center - Oklahoma City

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2024-02-05
Est. Completion 2027-04-01
Phase Phase 1

Sponsor

Quanta Therapeutics

3 total trials

What the Registry Record Tells You About NCT06227377

The ClinicalTrials.gov registry entry for NCT06227377 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 283-participant average among 125 other Solid Tumors trials with a reported enrollment target (12% lower). The listed sponsor is Quanta Therapeutics, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Solid Tumors appearing as the primary indexed condition, and to 2 interventions - of which Cetuximab is the first listed.

NCT06227377 reports 14 study locations spanning 11 distinct geographic areas - top geographies include Florida, New York, Texas.

Frequently Asked Questions

What is clinical trial NCT06227377 about?

NCT06227377 is a clinical study titled "QTX3034 in Patients With KRAS G12D Mutation". Phase 1 study to determine the safety and tolerability of QTX3034 as a single agent or in combination with cetuximab.

What is the current status of trial NCT06227377?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 250 participants. The study started on 2024-02-05. Estimated completion is 2027-04-01.

What conditions does trial NCT06227377 study?

This clinical trial studies the following conditions: Solid Tumors.

What interventions are being tested in trial NCT06227377?

The interventions under investigation include: Cetuximab (COMBINATION_PRODUCT), QTX3034 (DRUG).

Who is sponsoring clinical trial NCT06227377?

This trial is sponsored by Quanta Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06227377 being conducted?

This trial has 14 study locations across California, Colorado, Connecticut, Florida, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.