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NCT06222593 · ClinicalTrials.gov registry record · Phase 1
Study to Evaluate the Safety and Efficacy of Bicalutamide in Combination with Sunitinib in Patients with TKIs-resistant RCC
A Phase 1 study of Carcinoma, Renal Cell, sponsored by State University of New York at Buffalo.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 28
- Enrollment target
- 1
- Study location
NCT06222593: Recruiting Phase 1 study of Carcinoma, Renal Cell, sponsored by State University of New York at Buffalo.
NCT06222593 is a Phase 1 study of Carcinoma, Renal Cell that is actively recruiting participants, run by State University of New York at Buffalo. The registered enrollment target is 28 participants, below the 283-participant average among 34 other Carcinoma, Renal Cell trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06222593, a Phase 1 study of Carcinoma, Renal Cell, is actively recruiting participants, sponsored by State University of New York at Buffalo.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 28 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a Phase I/II open-label, efficacy and safety study of bicalutamide in combination with sunitinib in patients with advanced renal cell carcinoma (RCC) who have been treated with a receptor tyrosine kinase inhibitor (RTKI) and experienced disease progression.
Primary Outcome
Investigators will report the number of participants with treatment-related adverse events as assessed by CTCAE v4.0.
Conditions Studied
Interventions
- DRUG Bicalutamide in combination with Sunitinib
Study Locations (1)
New York
- UB/ Great Lakes Cancer Care - Buffalo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2024-10-01 |
| Est. Completion | 2027-07-01 |
| Phase | Phase 1 |
What NCT06222593 shows while recruiting
NCT06222593 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 283-participant average among 34 other Carcinoma, Renal Cell trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Carcinoma, Renal Cell appearing as the primary indexed condition, and to 1 intervention - of which Bicalutamide in combination with Sunitinib is the first listed.
NCT06222593 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06222593 about?
NCT06222593 is a clinical study titled "Study to Evaluate the Safety and Efficacy of Bicalutamide in Combination with Sunitinib in Patients with TKIs-resistant RCC". This is a Phase I/II open-label, efficacy and safety study of bicalutamide in combination with sunitinib in patients with advanced renal cell carcinoma (RCC) who have been treated with a receptor tyrosine kinase inhibitor (RTKI) and experienced disease progression.
What is the current status of trial NCT06222593?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2024-10-01. Estimated completion is 2027-07-01.
What conditions does trial NCT06222593 study?
This clinical trial studies the following conditions: Carcinoma, Renal Cell.
What interventions are being tested in trial NCT06222593?
The interventions under investigation include: Bicalutamide in combination with Sunitinib (DRUG).
Who is sponsoring clinical trial NCT06222593?
This trial is sponsored by State University of New York at Buffalo, which has 243 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06222593 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Carcinoma, Renal Cell
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06222593's enrollment target sits among peer trials
28 30th of 34 higher than 5 of 34 other Carcinoma, Renal Cell trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Carcinoma, Renal Cell trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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