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NCT06166745 · ClinicalTrials.gov registry record · NA
Efficacy of Sensi-IP Toothpaste in the Treatment of Dentinal Hypersensitivity Compared to a Sodium Fluoride Toothpaste
A NA study of Dentinal Hypersensitivity, sponsored by IR Scientific.
- Completed
- Registry status
- NA
- Development phase
- 46
- Enrollment target
- 1
- Study location
NCT06166745: Completed NA study of Dentinal Hypersensitivity, sponsored by IR Scientific.
NCT06166745 is a NA study of Dentinal Hypersensitivity that has completed, run by IR Scientific. The registered enrollment target is 46 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06166745, a NA study of Dentinal Hypersensitivity, has completed, sponsored by IR Scientific.
- COMPLETED
- Registry status
- NA
- Development phase
- 46 participants
- Enrollment target
- 1
- Study location
Study Summary
The study is designed as a prospective, randomized, parallel arm, double blinded, pilot clinical trial.The primary objective is to evaluate the efficacy of Sensi-IP +NaF as compared to a NaF toothpaste in the reduction of dentin hypersensitivity in adult participants over 14 days. Study endpoints include Evaporative Air blast Stimuli (Schiff Airblast Sensitivity Score), Tactile Stimuli (Yeaple probe Assessment), Visual Analogue Scale Evaporative Stimuli and the occurrence of adverse events. The study will include 2 study arms: 1. Sodium fluoride toothpaste with Sensi IP (N=23) and 2. Sodium fluoride toothpaste (N=23). Total of 46 participants (ages 18-80 years) with at least one hypersensitive tooth in 2 different quadrants which are anterior to the molars will be enrolled.
Primary Outcome
Schiff Airblast sensitivity score is mainly used to assess participant response to evaporated air stimuli. The scale is 0-3 and higher scores mean a worse outcome.
Conditions Studied
Interventions
- DEVICE Sensi-IP toothpaste
- DEVICE Sodium Fluoride Toothpaste
Study Locations (1)
Massachusetts
- The Forsyth Institute - Cambridge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2023-11-06 |
| Est. Completion | 2024-04-15 |
| Phase | NA |
What the finished NCT06166745 record still lists
NCT06166745 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Dentinal Hypersensitivity appearing as the primary indexed condition, and to 2 interventions - of which Sensi-IP toothpaste is the first listed.
NCT06166745 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06166745 about?
NCT06166745 is a clinical study titled "Efficacy of Sensi-IP Toothpaste in the Treatment of Dentinal Hypersensitivity Compared to a Sodium Fluoride Toothpaste". The study is designed as a prospective, randomized, parallel arm, double blinded, pilot clinical trial.The primary objective is to evaluate the efficacy of Sensi-IP +NaF as compared to a NaF toothpaste in the reduction of dentin hypersensitivity in adult participants over 14 days. Study endpoints in...
What is the current status of trial NCT06166745?
This trial is currently completed. It is a NA study. The enrollment target is 46 participants. The study started on 2023-11-06. Estimated completion is 2024-04-15.
What conditions does trial NCT06166745 study?
This clinical trial studies the following conditions: Dentinal Hypersensitivity.
What interventions are being tested in trial NCT06166745?
The interventions under investigation include: Sensi-IP toothpaste (DEVICE), Sodium Fluoride Toothpaste (DEVICE).
Who is sponsoring clinical trial NCT06166745?
This trial is sponsored by IR Scientific, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06166745 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06166745's enrollment target sits among peer trials
46 1402nd of 2000 higher than 590 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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