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NCT06151145 · ClinicalTrials.gov registry record · NA
Stepped Care for Weight Loss Maintenance
A NA study of Obesity, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- NA
- Development phase
- 180
- Enrollment target
- 1
- Study location
NCT06151145: Recruiting NA study of Obesity, sponsored by Johns Hopkins University.
NCT06151145 is a NA study of Obesity that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 180 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06151145, a NA study of Obesity, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- NA
- Development phase
- 180 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is a 3-group, parallel design, randomized controlled trial (RCT) in approximately 258 adults with obesity that will investigate whether a 16-week behavioral weight loss treatment and a 52-week stepped-care digital health intervention can improve the maintenance of a ≥ 5% weight loss. 16-week run-in (Phase 1). To qualify for randomization, participants must lose ≥ 5% of initial weight in the 16-week run-in. This loss will be achieved with the provision of weekly-group lifestyle counseling, which includes a partial meal replacement diet. 52-week randomized trial of 3 weight loss maintenance strategies (Phase 2): Participants who have achieved ≥ 5% weight loss during Phase 1 will be randomly assigned to 1 of 3 groups: 1. Participants in the Usual Care group will be emailed monthly educational modules with information on maintaining weight loss. 2. Participants in the SELF group will receive a wireless "smart" body weight scale and a wearable physical activity tracker, and daily text messages with tailored feedback to assist in weight loss maintenance. 3. Participants in the STEP group will be enrolled in an intervention that consists of 4 steps that are progressive and based on response to treatment. After 13 weeks at each step, participants who do not maintain a ≥5% weight loss or regain 2 percentage points of weight from the participants randomization value will move to a higher intensity step. Participants who maintain weight loss will stay at the same step.
Primary Outcome
Weight change (kg) for STEP versus usual care
Conditions Studied
Interventions
- BEHAVIORAL STEP
- BEHAVIORAL Usual care
- BEHAVIORAL SELF
Study Locations (1)
Maryland
- Johns Hopkins University - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2024-02-01 |
| Est. Completion | 2028-06 |
| Phase | NA |
What NCT06151145 shows while recruiting
NCT06151145 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 3 interventions - of which STEP is the first listed.
NCT06151145 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06151145 about?
NCT06151145 is a clinical study titled "Stepped Care for Weight Loss Maintenance". This study is a 3-group, parallel design, randomized controlled trial (RCT) in approximately 258 adults with obesity that will investigate whether a 16-week behavioral weight loss treatment and a 52-week stepped-care digital health intervention can improve the maintenance of a ≥ 5% weight loss. 16-...
What is the current status of trial NCT06151145?
This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2024-02-01. Estimated completion is 2028-06.
What conditions does trial NCT06151145 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT06151145?
The interventions under investigation include: STEP (BEHAVIORAL), Usual care (BEHAVIORAL), SELF (BEHAVIORAL).
Who is sponsoring clinical trial NCT06151145?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06151145 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06151145's enrollment target sits among peer trials
180 339th of 1053 higher than 709 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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