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NCT06139627 · ClinicalTrials.gov registry record · NA
Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy
A NA study of Lung Non-Small Cell Carcinoma and Stage III Lung Cancer AJCC v8, sponsored by City of Hope Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 180
- Enrollment target
- 3
- Study locations
NCT06139627: Recruiting NA study of Lung Non-Small Cell Carcinoma and Stage III Lung Cancer AJCC v8, sponsored by City of Hope Medical Center.
NCT06139627 is a NA study of Lung Non-Small Cell Carcinoma and Stage III Lung Cancer AJCC v8 that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 180 participants, above the 156-participant average among 47 other Lung Non-Small Cell Carcinoma trials with a reported enrollment target (15% higher). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06139627, a NA study of Lung Non-Small Cell Carcinoma and Stage III Lung Cancer AJCC v8, is actively recruiting participants, sponsored by City of Hope Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 180 participants
- Enrollment target
- 3
- Study locations
Study Summary
This clinical trial tests how well a geriatric assessment (GA) with GA-directed treatment recommendations, compared to GA with usual care, works in identifying risk factors, reducing chemotherapy radiation toxicity and functional decline, and improving the overall quality of life in older patients with non-small cell lung cancer (NSCLC). Older patients with lung cancer undergoing chemotherapy are at an increased risk of adverse outcomes including treatment toxicity and functional and physical consequences. This makes it very challenging for the physicians to balance the benefits against the risk of chemotherapy in older cancer patients. A geriatric assessment may be useful in identifying risk factors for chemotherapy radiation toxicity. Communicating these geriatric assessment findings and assessment-based recommendations to a patient's treating physicians may help them make more informed decisions about treatment options for patients. Making treatment decisions using GA-based recommendations may reduce adverse events and improve outcomes in patients receiving treatment for NSCLC.
Primary Outcome
Will be assessed by National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0 (NCI CTCAE v 5.0) for grade 3-5 non-hematologic toxicities. Chi-square test will be used to compare proportion of patients with grade 3-5 non-hematologic toxicity between two arms at 6 months after treatment initiation.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Best Practice
- OTHER Communication Intervention
- OTHER Comprehensive Geriatric Assessment
- OTHER Electronic Health Record Review
Study Locations (3)
California
- City of Hope Medical Center - Duarte
New York
- University of Rochester - Rochester
Ohio
- Ohio State University Comprehensive Cancer Center - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2024-05-21 |
| Est. Completion | 2026-07-19 |
| Phase | NA |
What NCT06139627 shows while recruiting
NCT06139627 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, above the 156-participant average among 47 other Lung Non-Small Cell Carcinoma trials with a reported enrollment target (15% higher).
The record links to 2 conditions, with Lung Non-Small Cell Carcinoma appearing as the primary indexed condition, and to 5 interventions - of which Biospecimen Collection is the first listed.
NCT06139627 reports a single indexed study location in California, New York, Ohio.
Frequently Asked Questions
What is clinical trial NCT06139627 about?
NCT06139627 is a clinical study titled "Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy". This clinical trial tests how well a geriatric assessment (GA) with GA-directed treatment recommendations, compared to GA with usual care, works in identifying risk factors, reducing chemotherapy radiation toxicity and functional decline, and improving the overall quality of life in older patients w...
What is the current status of trial NCT06139627?
This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2024-05-21. Estimated completion is 2026-07-19.
What conditions does trial NCT06139627 study?
This clinical trial studies the following conditions: Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8.
What interventions are being tested in trial NCT06139627?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Best Practice (OTHER), Communication Intervention (OTHER), Comprehensive Geriatric Assessment (OTHER), Electronic Health Record Review (OTHER).
Who is sponsoring clinical trial NCT06139627?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06139627 being conducted?
This trial has 3 study locations across California, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lung Non-Small Cell Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06139627's enrollment target sits among peer trials
180 9th of 47 higher than 39 of 47 other Lung Non-Small Cell Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Non-Small Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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