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NCT06983899 · ClinicalTrials.gov registry record · NA
Exercise Training for the Improvement of Immune Activity and Treatment Outcomes During Immunotherapy for Non-small Cell Lung Cancer, BOOST Trial
A NA study of Lung Non-Small Cell Carcinoma, sponsored by Fred Hutchinson Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06983899: Recruiting NA study of Lung Non-Small Cell Carcinoma, sponsored by Fred Hutchinson Cancer Center.
NCT06983899 is a NA study of Lung Non-Small Cell Carcinoma that is actively recruiting participants, run by Fred Hutchinson Cancer Center. The registered enrollment target is 100 participants, below the 158-participant average among 47 other Lung Non-Small Cell Carcinoma trials with a reported enrollment target (37% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06983899, a NA study of Lung Non-Small Cell Carcinoma, is actively recruiting participants, sponsored by Fred Hutchinson Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This clinical trial studies how well exercise training works in improving immune activity and treatment tolerance and response in patients with non-small cell lung cancer (NSCLC) who are receiving immunotherapy. Immunotherapy may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. The use of immunotherapy for the treatment of NSCLC has been rapidly increasing. Although immunotherapy have shown great potential in cancer therapy, not all patients benefit from this therapy and resistance to it can occur. This could be due to poor immune activity. It has been shown that exercise can enhance systemic immune activity in various ways. The exercise training used in this study is aerobic interval training. Aerobic interval training increases the heart rate and the body's use of oxygen and alternates short periods of intense aerobic exercise with less intense recovery periods. This may cause biological changes which may improve immune activity and treatment response in patients with NSCLC who are receiving immunotherapy.
Primary Outcome
The primary analysis will follow an intention-to-treat approach, using a two-sample t-test to compare changes in NLR from baseline between the groups.
Conditions Studied
Interventions
- OTHER Exercise Intervention
- OTHER Educational Intervention
- OTHER Electronic Health Record Review
- OTHER Aerobic Exercise
- PROCEDURE Dual X-ray Absorptiometry
Study Locations (1)
Washington
- Fred Hutch/University of Washington Cancer Consortium - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2026-01-28 |
| Est. Completion | 2028-05-31 |
| Phase | NA |
What NCT06983899 shows while recruiting
NCT06983899 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 158-participant average among 47 other Lung Non-Small Cell Carcinoma trials with a reported enrollment target (37% lower).
The record links to 1 condition, with Lung Non-Small Cell Carcinoma appearing as the primary indexed condition, and to 5 interventions - of which Exercise Intervention is the first listed.
NCT06983899 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT06983899 about?
NCT06983899 is a clinical study titled "Exercise Training for the Improvement of Immune Activity and Treatment Outcomes During Immunotherapy for Non-small Cell Lung Cancer, BOOST Trial". This clinical trial studies how well exercise training works in improving immune activity and treatment tolerance and response in patients with non-small cell lung cancer (NSCLC) who are receiving immunotherapy. Immunotherapy may induce changes in the body's immune system and may interfere with the ...
What is the current status of trial NCT06983899?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2026-01-28. Estimated completion is 2028-05-31.
What conditions does trial NCT06983899 study?
This clinical trial studies the following conditions: Lung Non-Small Cell Carcinoma.
What interventions are being tested in trial NCT06983899?
The interventions under investigation include: Exercise Intervention (OTHER), Educational Intervention (OTHER), Electronic Health Record Review (OTHER), Aerobic Exercise (OTHER), Dual X-ray Absorptiometry (PROCEDURE).
Who is sponsoring clinical trial NCT06983899?
This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06983899 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06983899's enrollment target sits among peer trials
100 14th of 47 higher than 32 of 47 other Lung Non-Small Cell Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lung Non-Small Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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