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NCT06096974 · ClinicalTrials.gov registry record · Phase 1

Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS

A Phase 1 study of Advanced Solid Tumors, sponsored by Shanghai YingLi Pharmaceutical Co..

Recruiting
Registry status
Phase 1
Development phase
60
Enrollment target
3
Study locations

NCT06096974 is a Phase 1 study of Advanced Solid Tumors that is actively recruiting participants, run by Shanghai YingLi Pharmaceutical Co.. The registered enrollment target is 60 participants, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (70% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT06096974, a Phase 1 study of Advanced Solid Tumors, is actively recruiting participants, sponsored by Shanghai YingLi Pharmaceutical Co..

RECRUITING
Registry status
Phase 1
Development phase
60 participants
Enrollment target
3
Study locations

Study Summary

This study will evaluate the safety, tolerability, drug levels, pharmacodynamic effects, and clinical activity of YL 17231 in patients with advanced solid tumors harboring mutations in KRAS, HRAS, or NRAS.

Conditions Studied

Interventions

  • DRUG YL-17231

Study Locations (3)

Ohio

  • The Lindner Center for Research & Education at The Christ Hospital - Cincinnati

Texas

  • MD Anderson Cancer Center - Houston

Utah

  • Huntsman Cancer Institute and Hospital, University of Utah - Salt Lake City

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2023-10-24
Est. Completion 2026-04
Phase Phase 1

What the Registry Record Tells You About NCT06096974

The ClinicalTrials.gov registry entry for NCT06096974 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (70% lower). The listed sponsor is Shanghai YingLi Pharmaceutical Co., which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which YL-17231 is the first listed.

NCT06096974 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Ohio, Texas, Utah.

Frequently Asked Questions

What is clinical trial NCT06096974 about?

NCT06096974 is a clinical study titled "Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS". This study will evaluate the safety, tolerability, drug levels, pharmacodynamic effects, and clinical activity of YL 17231 in patients with advanced solid tumors harboring mutations in KRAS, HRAS, or NRAS.

What is the current status of trial NCT06096974?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2023-10-24. Estimated completion is 2026-04.

What conditions does trial NCT06096974 study?

This clinical trial studies the following conditions: Advanced Solid Tumors.

What interventions are being tested in trial NCT06096974?

The interventions under investigation include: YL-17231 (DRUG).

Who is sponsoring clinical trial NCT06096974?

This trial is sponsored by Shanghai YingLi Pharmaceutical Co., which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06096974 being conducted?

This trial has 3 study locations across Ohio, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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