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NCT06079034 · ClinicalTrials.gov registry record

Impact of Cannulation Strategy on Neurologic Injury in Infants With Respiratory Failure

A clinical trial, sponsored by University of Michigan.

Completed
Registry status
5,058
Enrollment target

NCT06079034: Completed study, sponsored by University of Michigan.

NCT06079034 is a clinical trial that has completed, run by University of Michigan. The registered enrollment target is 5,058 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06079034 has completed, sponsored by University of Michigan.

COMPLETED
Registry status
5,058 participants
Enrollment target

Study Summary

There has been increasing use of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) for infants with respiratory failure, up to 92% of neonatal respiratory support in 2021. This study seeks to leverage the increased use of VA ECMO in this cohort to enrich an evaluation of the differences in rate of intracranial hemorrhage and ischemic stroke between venovenous (VV) and VA ECMO among infants with respiratory failure where clinicians may choose either strategy. This project is a retrospective review of data in the ELSO registry.

Primary Outcome

The outcome will be the composite occurrence of neurologic injury (ischemic stroke, intracranial hemorrhage, and brain death) that arises during critical illness supported by extracorporeal life support (ECLS) as reported to the Extracorporeal Life Support Organization (ELSO) registry, coded as a 0/1 variable (0 = no occurrence was reported during or after ECMO; 1 = one or more occurrence was reported).

Interventions

  • PROCEDURE Venovenous ECMO
  • PROCEDURE Venoarterial ECMO

Trial Details

FieldValue
Enrollment Target 5,058 participants
Start Date 2023-10-18
Est. Completion 2023-12-12
University of Michigan

1,327 total trials

What the finished NCT06079034 record still lists

NCT06079034 is an observational study that tracks outcomes without assigning an intervention. Its 5,058 participants enrollment target places it among the larger protocols in the corpus.

The record links to 0 conditions, and to 2 interventions - of which Venovenous ECMO is the first listed.

NCT06079034 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06079034 about?

NCT06079034 is a clinical study titled "Impact of Cannulation Strategy on Neurologic Injury in Infants With Respiratory Failure". There has been increasing use of venoarterial (VA) extracorporeal membrane oxygenation (ECMO) for infants with respiratory failure, up to 92% of neonatal respiratory support in 2021. This study seeks to leverage the increased use of VA ECMO in this cohort to enrich an evaluation of the differences i...

What is the current status of trial NCT06079034?

This trial is currently completed. The enrollment target is 5,058 participants. The study started on 2023-10-18. Estimated completion is 2023-12-12.

What interventions are being tested in trial NCT06079034?

The interventions under investigation include: Venovenous ECMO (PROCEDURE), Venoarterial ECMO (PROCEDURE).

Who is sponsoring clinical trial NCT06079034?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT06079034, the US trial registry maintained by the National Library of Medicine. NCT06079034 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.