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NCT06817889 · ClinicalTrials.gov registry record · Phase 2

Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

A Phase 2 study of Hematopoietic and Lymphatic System Neoplasm and Autoimmune Disease, sponsored by Fred Hutchinson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target
3
Study locations

NCT06817889: Recruiting Phase 2 study of Hematopoietic and Lymphatic System Neoplasm and Autoimmune Disease, sponsored by Fred Hutchinson Cancer Center.

NCT06817889 is a Phase 2 study of Hematopoietic and Lymphatic System Neoplasm and Autoimmune Disease that is actively recruiting participants, run by Fred Hutchinson Cancer Center. The registered enrollment target is 60 participants, below the 482-participant average among 62 other Hematopoietic and Lymphatic System Neoplasm trials with a reported enrollment target (88% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06817889, a Phase 2 study of Hematopoietic and Lymphatic System Neoplasm and Autoimmune Disease, is actively recruiting participants, sponsored by Fred Hutchinson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target
3
Study locations

Study Summary

This phase II trial tests how well remdesivir works for treatment of respiratory syncytial virus (RSV) infection of the upper respiratory tract in patients receiving cellular or bispecific antibody therapy. Cellular or bispecific antibody therapies cause suppression of the immune system, making infections more frequent and reducing the body's ability to fight the infections. RSV infections are one of the most common respiratory infections in immunocompromised individuals and can cause significant pneumonia and even death. Remdesivir is in a class of medications called antivirals. It works by stopping viruses from spreading in the body.

Primary Outcome

Will be estimated with 95% Wilson confidence intervals.

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Survey Administration
  • DRUG Remdesivir
  • PROCEDURE Nasal Swab

Study Locations (3)

California

  • City of Hope Comprehensive Cancer Center - Duarte

Texas

  • MD Anderson Cancer Center - Houston

Washington

  • Fred Hutch/University of Washington Cancer Consortium - Seattle

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-12-23
Est. Completion 2027-11-30
Phase Phase 2
Fred Hutchinson Cancer Center

483 total trials

What NCT06817889 shows while recruiting

NCT06817889 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 482-participant average among 62 other Hematopoietic and Lymphatic System Neoplasm trials with a reported enrollment target (88% lower).

The record links to 3 conditions, with Hematopoietic and Lymphatic System Neoplasm appearing as the primary indexed condition, and to 4 interventions - of which Biospecimen Collection is the first listed.

NCT06817889 reports a single indexed study location in California, Texas, Washington.

Frequently Asked Questions

What is clinical trial NCT06817889 about?

NCT06817889 is a clinical study titled "Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals". This phase II trial tests how well remdesivir works for treatment of respiratory syncytial virus (RSV) infection of the upper respiratory tract in patients receiving cellular or bispecific antibody therapy. Cellular or bispecific antibody therapies cause suppression of the immune system, making infe...

What is the current status of trial NCT06817889?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2025-12-23. Estimated completion is 2027-11-30.

What conditions does trial NCT06817889 study?

This clinical trial studies the following conditions: Hematopoietic and Lymphatic System Neoplasm, Autoimmune Disease, Respiratory Syncytial Virus Infection.

What interventions are being tested in trial NCT06817889?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Survey Administration (OTHER), Remdesivir (DRUG), Nasal Swab (PROCEDURE).

Who is sponsoring clinical trial NCT06817889?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06817889 being conducted?

This trial has 3 study locations across California, Texas, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hematopoietic and Lymphatic System Neoplasm

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06817889's enrollment target sits among peer trials

60 32nd of 62 higher than 28 of 62 other Hematopoietic and Lymphatic System Neoplasm trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hematopoietic and Lymphatic System Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06817889, the US trial registry maintained by the National Library of Medicine. NCT06817889 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.