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NCT06025747 · ClinicalTrials.gov registry record · Phase 1
Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma
A Phase 1 study of Retroperitoneal Sarcoma, sponsored by University of Washington.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT06025747: Recruiting Phase 1 study of Retroperitoneal Sarcoma, sponsored by University of Washington.
NCT06025747 is a Phase 1 study of Retroperitoneal Sarcoma that is actively recruiting participants, run by University of Washington. The registered enrollment target is 18 participants, below the 413-participant average among 6 other Retroperitoneal Sarcoma trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06025747, a Phase 1 study of Retroperitoneal Sarcoma, is actively recruiting participants, sponsored by University of Washington.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase I trial tests the safety, side effects, and best dose of abemaciclib and how well it works with radiation therapy before surgery in treating patients with high-risk adipocytic retroperitoneal sarcoma. Abemaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving abemaciclib together with radiation therapy before surgery may shrink tumors in patients with high-risk adipocytic retroperitoneal sarcoma.
Conditions Studied
Interventions
- PROCEDURE Computed Tomography
- PROCEDURE Magnetic Resonance Imaging
- RADIATION Radiation Therapy
- DRUG Abemaciclib
- PROCEDURE Therapeutic Surgical Procedure
Study Locations (1)
Washington
- Fred Hutch/University of Washington Cancer Consortium - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2025-03-19 |
| Est. Completion | 2029-03-03 |
| Phase | Phase 1 |
What NCT06025747 shows while recruiting
NCT06025747 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 413-participant average among 6 other Retroperitoneal Sarcoma trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Retroperitoneal Sarcoma appearing as the primary indexed condition, and to 5 interventions - of which Computed Tomography is the first listed.
NCT06025747 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT06025747 about?
NCT06025747 is a clinical study titled "Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma". This phase I trial tests the safety, side effects, and best dose of abemaciclib and how well it works with radiation therapy before surgery in treating patients with high-risk adipocytic retroperitoneal sarcoma. Abemaciclib may stop the growth of tumor cells by blocking some of the enzymes needed fo...
What is the current status of trial NCT06025747?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2025-03-19. Estimated completion is 2029-03-03.
What conditions does trial NCT06025747 study?
This clinical trial studies the following conditions: Retroperitoneal Sarcoma.
What interventions are being tested in trial NCT06025747?
The interventions under investigation include: Computed Tomography (PROCEDURE), Magnetic Resonance Imaging (PROCEDURE), Radiation Therapy (RADIATION), Abemaciclib (DRUG), Therapeutic Surgical Procedure (PROCEDURE).
Who is sponsoring clinical trial NCT06025747?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06025747 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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