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NCT04189783 · ClinicalTrials.gov registry record · Phase 2
Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)
A Phase 2 study of Retroperitoneal Sarcoma, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- Phase 2
- Development phase
- 113
- Enrollment target
- 1
- Study location
NCT04189783: Active Phase 2 study of Retroperitoneal Sarcoma, sponsored by M.D. Anderson Cancer Center.
NCT04189783 is a Phase 2 study of Retroperitoneal Sarcoma that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 113 participants, below the 397-participant average among 6 other Retroperitoneal Sarcoma trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04189783, a Phase 2 study of Retroperitoneal Sarcoma, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 113 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase II trial studies how well a repeat or single liposomal bupivacaine injection (quadratus lumborum block) works in reducing opioid prescriptions after surgery in patients with retroperitoneal sarcoma. Liposomal bupivacaine is a numbing medication. Giving a second injection block may decrease dependency on opioid medications for pain relief after surgery and prevent long-term use and addiction.
Primary Outcome
After sarcoma surgery, our historical discharge opioid prescription was a median of 300mg oral morphine equivalents (OME) in 2016-2018, with 5% patients discharged opioid-free. The primary objective of this study was to compare 2 novel opioid-reduction bundles to increase the proportion of opioid-free patients.
Conditions Studied
Interventions
- OTHER Questionnaire Administration
- DRUG Liposomal Bupivacaine
- DRUG Quadratus Lumborum Block
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 113 participants |
| Start Date | 2020-06-08 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 2 |
What the registry record for NCT04189783 still lists
NCT04189783 is an interventional study that assigns participants to a tested intervention. The registered 113 participants enrollment target is mid-sized for trials with a published cap, below the 397-participant average among 6 other Retroperitoneal Sarcoma trials with a reported enrollment target (72% lower).
The record links to 1 condition, with Retroperitoneal Sarcoma appearing as the primary indexed condition, and to 3 interventions - of which Questionnaire Administration is the first listed.
NCT04189783 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04189783 about?
NCT04189783 is a clinical study titled "Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)". This phase II trial studies how well a repeat or single liposomal bupivacaine injection (quadratus lumborum block) works in reducing opioid prescriptions after surgery in patients with retroperitoneal sarcoma. Liposomal bupivacaine is a numbing medication. Giving a second injection block may decreas...
What is the current status of trial NCT04189783?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 113 participants. The study started on 2020-06-08. Estimated completion is 2026-12-31.
What conditions does trial NCT04189783 study?
This clinical trial studies the following conditions: Retroperitoneal Sarcoma.
What interventions are being tested in trial NCT04189783?
The interventions under investigation include: Questionnaire Administration (OTHER), Liposomal Bupivacaine (DRUG), Quadratus Lumborum Block (DRUG).
Who is sponsoring clinical trial NCT04189783?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04189783 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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