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NCT05995223 · ClinicalTrials.gov registry record · NA

Oxygen Uptake Kinetics During Submaximal Exercise in Adults With Down Syndrome

A NA study of Down Syndrome, sponsored by University of Nevada, Las Vegas.

Completed
Registry status
NA
Development phase
28
Enrollment target
1
Study location

NCT05995223 is a NA study of Down Syndrome that has completed, run by University of Nevada, Las Vegas. The registered enrollment target is 28 participants, below the 2,471-participant average among 54 other Down Syndrome trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05995223, a NA study of Down Syndrome, has completed, sponsored by University of Nevada, Las Vegas.

COMPLETED
Registry status
NA
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

This study aims to compare the rate at which oxygen uptake adapts to submaximal, moderate intensity exercise (oxygen uptake kinetics) between adults with and without Down syndrome, to determine the contribution of oxygen uptake kinetics to exercise intolerance of adults with Down syndrome. Additionally, the study will investigate the role of oxygen delivery (by the cardiovascular circuit) and oxygen utilization (in the mitochondria) on the oxygen uptake kinetics of adults with Down syndrome to identify specific areas which adults with Down syndrome could benefit from targeting during exercise training. Overall, this study aims to contribute to the knowledge on the exercise capacity of adults with Down syndrome, in order to improve the way adults with Down syndrome participate in and benefit from exercise. Participants will perform a maximal exercise test on a treadmill, and walk on a treadmill at a submaximal, moderate intensity speed and incline, during which oxygen uptake at the lungs, cardiac output, and oxygen utilization in the muscle will be measured.

Conditions Studied

Interventions

  • OTHER Submaximal exercise protocol

Study Locations (1)

Nevada

  • University of Nevada, Las Vegas - Las Vegas

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2023-10-04
Est. Completion 2024-06-27
Phase NA

Sponsor

University of Nevada, Las Vegas

52 total trials

What the Registry Record Tells You About NCT05995223

The ClinicalTrials.gov registry entry for NCT05995223 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,471-participant average among 54 other Down Syndrome trials with a reported enrollment target (99% lower). The listed sponsor is University of Nevada, Las Vegas, which has 52 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Down Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Submaximal exercise protocol is the first listed.

NCT05995223 reports 1 study location spanning 1 distinct geographic area - top geographies include Nevada.

Frequently Asked Questions

What is clinical trial NCT05995223 about?

NCT05995223 is a clinical study titled "Oxygen Uptake Kinetics During Submaximal Exercise in Adults With Down Syndrome". This study aims to compare the rate at which oxygen uptake adapts to submaximal, moderate intensity exercise (oxygen uptake kinetics) between adults with and without Down syndrome, to determine the contribution of oxygen uptake kinetics to exercise intolerance of adults with Down syndrome. Additiona...

What is the current status of trial NCT05995223?

This trial is currently completed. It is a NA study. The enrollment target is 28 participants. The study started on 2023-10-04. Estimated completion is 2024-06-27.

What conditions does trial NCT05995223 study?

This clinical trial studies the following conditions: Down Syndrome.

What interventions are being tested in trial NCT05995223?

The interventions under investigation include: Submaximal exercise protocol (OTHER).

Who is sponsoring clinical trial NCT05995223?

This trial is sponsored by University of Nevada, Las Vegas, which has 52 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05995223 being conducted?

This trial has 1 study location across Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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