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NCT05992831 · ClinicalTrials.gov registry record · NA

Transcranial Magnetic Stimulation for MCI

A NA study of Depression and Mild Cognitive Impairment, sponsored by Medical University of South Carolina.

Recruiting
Registry status
NA
Development phase
60
Enrollment target
1
Study location

NCT05992831 is a NA study of Depression and Mild Cognitive Impairment that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 60 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05992831, a NA study of Depression and Mild Cognitive Impairment, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
NA
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The goal of this phase II study is to establish the dose-response curves of a safe and clinically feasible non-invasive brain stimulation technique (accelerated Transcranial Magnetic Stimulation (TMS)) to improve both depression and cognitive function in Mild Cognitive Impairment (MCI) patients with comorbid depression. It is known that TMS can effectively treat depression. Identifying the right dose of accelerated TMS in MCI patients is necessary prior to designing subsequent trials to determine efficacy. These results will inform future clinical trials of accelerated TMS for MCI, with the long-term goal of developing an efficacious treatment to prevent dementia.

Interventions

  • DEVICE Sham Comparator
  • DEVICE Accelerated iTBS

Study Locations (1)

South Carolina

  • Medical University of South Carolina - Charleston

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2024-06-18
Est. Completion 2028-04-30
Phase NA

What the Registry Record Tells You About NCT05992831

The ClinicalTrials.gov registry entry for NCT05992831 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (92% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Sham Comparator is the first listed.

NCT05992831 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.

Frequently Asked Questions

What is clinical trial NCT05992831 about?

NCT05992831 is a clinical study titled "Transcranial Magnetic Stimulation for MCI". The goal of this phase II study is to establish the dose-response curves of a safe and clinically feasible non-invasive brain stimulation technique (accelerated Transcranial Magnetic Stimulation (TMS)) to improve both depression and cognitive function in Mild Cognitive Impairment (MCI) patients with...

What is the current status of trial NCT05992831?

This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-06-18. Estimated completion is 2028-04-30.

What conditions does trial NCT05992831 study?

This clinical trial studies the following conditions: Depression, Mild Cognitive Impairment.

What interventions are being tested in trial NCT05992831?

The interventions under investigation include: Sham Comparator (DEVICE), Accelerated iTBS (DEVICE).

Who is sponsoring clinical trial NCT05992831?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05992831 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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