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NCT05987644 · ClinicalTrials.gov registry record · Phase 1
Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements
A Phase 1 study of Lung Cancer and NSCLC, sponsored by Joshua Palmer.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 56
- Enrollment target
- 3
- Study locations
NCT05987644 is a Phase 1 study of Lung Cancer and NSCLC that is actively recruiting participants, run by Joshua Palmer. The registered enrollment target is 56 participants, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (94% lower). The trial reports 3 study locations across 3 states.
The verdict
NCT05987644, a Phase 1 study of Lung Cancer and NSCLC, is actively recruiting participants, sponsored by Joshua Palmer.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 56 participants
- Enrollment target
- 3
- Study locations
Study Summary
This study will consist of a Phase 1b and Phase 2 portion. The Phase 1b portion will enroll first followed by the Phase 2 portion. Each cycle of treatment = 28 days. Subjects will receive alectinib twice daily. Those in the Phase 1b portion will receive alectinib alone. Those in Phase 2 Arm A will receive alectinib alone. Those in Phase 2, Arm B will receive SRS + alectinib. A maximum of 25 cycles (2 years) of alectinib may be administered on study.
Conditions Studied
Interventions
- RADIATION Stereotactic Radiosurgery
- DRUG Alectinib
Study Locations (3)
California
- Stanford University - Stanford
Colorado
- University of Colorado Cancer Center - Aurora
Ohio
- Ohio State University Comprehensive Cancer Center - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2024-03-07 |
| Est. Completion | 2027-06 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05987644
The ClinicalTrials.gov registry entry for NCT05987644 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 936-participant average among 409 other Lung Cancer trials with a reported enrollment target (94% lower). The listed sponsor is Joshua Palmer, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which Stereotactic Radiosurgery is the first listed.
NCT05987644 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Colorado, Ohio.
Frequently Asked Questions
What is clinical trial NCT05987644 about?
NCT05987644 is a clinical study titled "Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements". This study will consist of a Phase 1b and Phase 2 portion. The Phase 1b portion will enroll first followed by the Phase 2 portion. Each cycle of treatment = 28 days. Subjects will receive alectinib twice daily. Those in the Phase 1b portion will receive alectinib alone. Those in Phase 2 Arm A will ...
What is the current status of trial NCT05987644?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 56 participants. The study started on 2024-03-07. Estimated completion is 2027-06.
What conditions does trial NCT05987644 study?
This clinical trial studies the following conditions: Lung Cancer, NSCLC, Brain Metastases.
What interventions are being tested in trial NCT05987644?
The interventions under investigation include: Stereotactic Radiosurgery (RADIATION), Alectinib (DRUG).
Who is sponsoring clinical trial NCT05987644?
This trial is sponsored by Joshua Palmer, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05987644 being conducted?
This trial has 3 study locations across California, Colorado, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.