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NCT05986578 · ClinicalTrials.gov registry record · NA
Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder
A NA study of Cocaine Use Disorder, sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT05986578: Recruiting NA study of Cocaine Use Disorder, sponsored by The University of Texas Health Science Center, Houston.
NCT05986578 is a NA study of Cocaine Use Disorder that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 75 participants, below the 101-participant average among 26 other Cocaine Use Disorder trials with a reported enrollment target (26% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05986578, a NA study of Cocaine Use Disorder, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to assess effects of intermittent theta burst stimulation (iTBS) to left dorsolateral prefrontal cortex (dlPFC) and dorsomedial prefrontal cortex (dmPFC) compared to sham on electrophysiological indices of reward sensitivity and motivated attention in adults with cocaine use disorder.
Primary Outcome
The Doors Task will be used to elicit the RewP component, representing reward sensitivity. The task is a guessing game, where participants guess which door contains a reward behind it. After selecting a door, the participants are notified if they found the prize by a green arrow pointing up or if they did not find the prize by a red arrow pointing down.
Conditions Studied
Interventions
- DEVICE TMS to dmPFC
- DEVICE TMS to dlPFC
- DEVICE Sham iTBS
Study Locations (1)
Texas
- The University of Texas Health Science Center at Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2024-11-08 |
| Est. Completion | 2028-06-30 |
| Phase | NA |
What NCT05986578 shows while recruiting
NCT05986578 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 101-participant average among 26 other Cocaine Use Disorder trials with a reported enrollment target (26% lower).
The record links to 1 condition, with Cocaine Use Disorder appearing as the primary indexed condition, and to 3 interventions - of which TMS to dmPFC is the first listed.
NCT05986578 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05986578 about?
NCT05986578 is a clinical study titled "Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder". The purpose of this study is to assess effects of intermittent theta burst stimulation (iTBS) to left dorsolateral prefrontal cortex (dlPFC) and dorsomedial prefrontal cortex (dmPFC) compared to sham on electrophysiological indices of reward sensitivity and motivated attention in adults with cocaine...
What is the current status of trial NCT05986578?
This trial is currently recruiting. It is a NA study. The enrollment target is 75 participants. The study started on 2024-11-08. Estimated completion is 2028-06-30.
What conditions does trial NCT05986578 study?
This clinical trial studies the following conditions: Cocaine Use Disorder.
What interventions are being tested in trial NCT05986578?
The interventions under investigation include: TMS to dmPFC (DEVICE), TMS to dlPFC (DEVICE), Sham iTBS (DEVICE).
Who is sponsoring clinical trial NCT05986578?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05986578 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cocaine Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05986578's enrollment target sits among peer trials
75 11th of 26 higher than 15 of 26 other Cocaine Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cocaine Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Contingency Management for Drug Use: Does Age Matter?
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Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting
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-
Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder (Pilot Study)
COMPLETED · NA
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