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NCT05631548 · ClinicalTrials.gov registry record · NA

Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder (Pilot Study)

A NA study of Cocaine Use Disorder, sponsored by The University of Texas Health Science Center, Houston.

Completed
Registry status
NA
Development phase
6
Enrollment target
1
Study location

NCT05631548: Completed NA study of Cocaine Use Disorder, sponsored by The University of Texas Health Science Center, Houston.

NCT05631548 is a NA study of Cocaine Use Disorder that has completed, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 6 participants, below the 104-participant average among 26 other Cocaine Use Disorder trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05631548, a NA study of Cocaine Use Disorder, has completed, sponsored by The University of Texas Health Science Center, Houston.

COMPLETED
Registry status
NA
Development phase
6 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to assess the effects of active intermittent theta burst stimulation (iTBS) to dorsomedial prefrontal cortex (dmPFC) on electroencephalogram (EEG) measures of reward sensitivity and cue reactivity and cocaine craving in cocaine users

Primary Outcome

The Doors Task will be used to elicit the Reward Potential (RewP) component, representing reward sensitivity. The task is a guessing game, where participants guess which door contains a reward behind it. After selecting a door, the participants are notified if they found the prize by a green arrow pointing up or if they did not find the prize by a red arrow pointing down. The amplitude of the RewP in microvolts in response to feedback is reported.

Conditions Studied

Cocaine Use Disorder

Interventions

  • DEVICE Sham iTBS
  • DEVICE iTBS to dmPFC

Study Locations (1)

Texas

  • The University of Texas Health Science Center at Houston - Houston

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2023-02-23
Est. Completion 2023-08-02
Phase NA
The University of Texas Health Science Center, Houston

732 total trials

What the finished NCT05631548 record still lists

NCT05631548 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 104-participant average among 26 other Cocaine Use Disorder trials with a reported enrollment target (94% lower).

The record links to 1 condition, with Cocaine Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Sham iTBS is the first listed.

NCT05631548 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05631548 about?

NCT05631548 is a clinical study titled "Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder (Pilot Study)". The purpose of this study is to assess the effects of active intermittent theta burst stimulation (iTBS) to dorsomedial prefrontal cortex (dmPFC) on electroencephalogram (EEG) measures of reward sensitivity and cue reactivity and cocaine craving in cocaine users

What is the current status of trial NCT05631548?

This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2023-02-23. Estimated completion is 2023-08-02.

What conditions does trial NCT05631548 study?

This clinical trial studies the following conditions: Cocaine Use Disorder.

What interventions are being tested in trial NCT05631548?

The interventions under investigation include: Sham iTBS (DEVICE), iTBS to dmPFC (DEVICE).

Who is sponsoring clinical trial NCT05631548?

This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05631548 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Cocaine Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05631548's enrollment target sits among peer trials

6 27th of 26 the lowest of 26 other Cocaine Use Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cocaine Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT05631548, the US trial registry maintained by the National Library of Medicine. NCT05631548 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.