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NCT05982925 · ClinicalTrials.gov registry record
Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
A clinical trial, sponsored by Icahn School of Medicine at Mount Sinai.
- Recruiting
- Registry status
- 170
- Enrollment target
NCT05982925 is a clinical trial that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 170 participants.
The verdict
NCT05982925 is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.
- RECRUITING
- Registry status
- 170 participants
- Enrollment target
Study Summary
In this protocol, a combination of MRI, blood, and cerebrospinal fluid (CSF) analysis will be used to understand the natural history, underlying immunologic mechanisms, and clinical implications of central nervous system (CNS) lesions, in particular lesions in the cerebral cortex, in multiple sclerosis (MS) and other inflammatory and autoimmune disorders affecting the CNS. Patients with these disorders, as well as healthy controls, will undergo baseline clinical evaluation and testing, bloodwork, and MRI, with follow up clinical evaluation, bloodwork, and MRI at years 1, 3, and 6. Additional MRIs may be performed in patients with possible new lesion formation or to compare MRI techniques. Lumbar puncture will be performed on participants who are not currently being treated with disease modifying therapies and who are willing to undergo the procedure.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 2022-05-06 |
| Est. Completion | 2034-07-31 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05982925
The ClinicalTrials.gov registry entry for NCT05982925 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 170 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Icahn School of Medicine at Mount Sinai, which has 708 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT05982925 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05982925 about?
NCT05982925 is a clinical study titled "Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders". In this protocol, a combination of MRI, blood, and cerebrospinal fluid (CSF) analysis will be used to understand the natural history, underlying immunologic mechanisms, and clinical implications of central nervous system (CNS) lesions, in particular lesions in the cerebral cortex, in multiple sclero...
What is the current status of trial NCT05982925?
This trial is currently recruiting. The enrollment target is 170 participants. The study started on 2022-05-06. Estimated completion is 2034-07-31.
Who is sponsoring clinical trial NCT05982925?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
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