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NCT05980117 · ClinicalTrials.gov registry record · Phase 4

Remimazolam for Cataract Surgery

A Phase 4 study of Cognitive Impairment and Cataract Surgery, sponsored by University of California, Los Angeles.

Recruiting
Registry status
Phase 4
Development phase
120
Enrollment target
1
Study location

NCT05980117 is a Phase 4 study of Cognitive Impairment and Cataract Surgery that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 120 participants, below the 665-participant average among 105 other Cognitive Impairment trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05980117, a Phase 4 study of Cognitive Impairment and Cataract Surgery, is actively recruiting participants, sponsored by University of California, Los Angeles.

RECRUITING
Registry status
Phase 4
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to assess any post operative cognitive changes following benzodiazepine administration during cataract surgery. The investigators will compare effects of Midazolam vs. Remimazolam on cognition at the time of discharge from the post operative care unit and the next day following surgery. Cognitive changes will be assessed by administration of Montreal Cognitive Assessment (MoCA). Participants will: 1. Complete MoCA testing prior to surgery 2. Randomize in either Midazolam or study drug Remimazolam 3. Complete MoCA testing after surgery at the time of discharge in the post anesthesia care unit and the next day of surgery at the time of post operative surgical visit. 4. Complete Patient Satisfaction Survey at the time of discharge from the Post Anesthesia Care Unit (PACU)

Interventions

  • DRUG Midazolam
  • DRUG Remimazolam

Study Locations (1)

California

  • Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine - Los Angeles

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2025-03-10
Est. Completion 2026-01
Phase Phase 4

What the Registry Record Tells You About NCT05980117

The ClinicalTrials.gov registry entry for NCT05980117 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 665-participant average among 105 other Cognitive Impairment trials with a reported enrollment target (82% lower). The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which Midazolam is the first listed.

NCT05980117 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05980117 about?

NCT05980117 is a clinical study titled "Remimazolam for Cataract Surgery". The goal of this study is to assess any post operative cognitive changes following benzodiazepine administration during cataract surgery. The investigators will compare effects of Midazolam vs. Remimazolam on cognition at the time of discharge from the post operative care unit and the next day follo...

What is the current status of trial NCT05980117?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 120 participants. The study started on 2025-03-10. Estimated completion is 2026-01.

What conditions does trial NCT05980117 study?

This clinical trial studies the following conditions: Cognitive Impairment, Cataract Surgery.

What interventions are being tested in trial NCT05980117?

The interventions under investigation include: Midazolam (DRUG), Remimazolam (DRUG).

Who is sponsoring clinical trial NCT05980117?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05980117 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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