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NCT05948930 · ClinicalTrials.gov registry record · NA
Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment
A NA study of Mild Cognitive Impairment, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- NA
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT05948930: Recruiting NA study of Mild Cognitive Impairment, sponsored by University of Maryland, Baltimore.
NCT05948930 is a NA study of Mild Cognitive Impairment that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 90 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05948930, a NA study of Mild Cognitive Impairment, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
The prevalence of dementia will double in the next three decades in the U.S.; effective treatment or prevention for dementia is urgently needed. The current exploratory project aims to evaluate and understand how the brain and cognition may improve after a 12-week intervention that combines brain training and aerobic exercise training to improve brain function, both in those with mild cognitive impairment (some with possible prodromal Alzheimer's disease) and with healthy aging. Findings from this pilot project will guide and refine the development of a future larger clinical trial that aligns with the goals of the National Alzheimer's Plan of Action (NAPA), especially regarding "Prevent and Effectively Treat Alzheimer's Disease (AD) by 2025.
Primary Outcome
Changes in brain volume measures from T1-weighted images (volumes in mm3)
Conditions Studied
Interventions
- BEHAVIORAL Progressive aerobic exercise
- BEHAVIORAL Adaptive cognitive training
- BEHAVIORAL Combined
Study Locations (1)
Maryland
- University of Maryland Baltimore - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2024-01-08 |
| Est. Completion | 2026-08-07 |
| Phase | NA |
What NCT05948930 shows while recruiting
NCT05948930 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 3 interventions - of which Progressive aerobic exercise is the first listed.
NCT05948930 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05948930 about?
NCT05948930 is a clinical study titled "Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment". The prevalence of dementia will double in the next three decades in the U.S.; effective treatment or prevention for dementia is urgently needed. The current exploratory project aims to evaluate and understand how the brain and cognition may improve after a 12-week intervention that combines brain tr...
What is the current status of trial NCT05948930?
This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2024-01-08. Estimated completion is 2026-08-07.
What conditions does trial NCT05948930 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment.
What interventions are being tested in trial NCT05948930?
The interventions under investigation include: Progressive aerobic exercise (BEHAVIORAL), Adaptive cognitive training (BEHAVIORAL), Combined (BEHAVIORAL).
Who is sponsoring clinical trial NCT05948930?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05948930 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Mild Cognitive Impairment
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05948930's enrollment target sits among peer trials
90 96th of 205 higher than 109 of 205 other Mild Cognitive Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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