Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05111743 · ClinicalTrials.gov registry record
Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (Komodo Health)
A clinical trial of Age-related Macular Degeneration (AMD), sponsored by Novartis Pharmaceuticals.
- Completed
- Registry status
- 9,261
- Enrollment target
- 1
- Study location
NCT05111743: Completed study of Age-related Macular Degeneration (AMD), sponsored by Novartis Pharmaceuticals.
NCT05111743 is a study of Age-related Macular Degeneration (AMD) that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 9,261 participants, below the 100,599-participant average among 7 other Age-related Macular Degeneration (AMD) trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05111743, a study of Age-related Macular Degeneration (AMD), has completed, sponsored by Novartis Pharmaceuticals.
- COMPLETED
- Registry status
- 9,261 participants
- Enrollment target
- 1
- Study location
Study Summary
This study was a retrospective cohort study of patients to assess the early insights into real-world safety among wet AMD patients initiating brolucizumab. Evidence was generated to describe their patient characteristics and clinical outcomes. The study was conducted using the Komodo Healthcare Map.
Primary Outcome
To assess IOI events observed after starting treatment with brolucizumab
Conditions Studied
Interventions
- DRUG Brolucizumab
Study Locations (1)
New Jersey
- Novartis Investigative Site - East Hanover
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9,261 participants |
| Start Date | 2020-06-17 |
| Est. Completion | 2020-12-18 |
What the finished NCT05111743 record still lists
NCT05111743 is an observational study that tracks outcomes without assigning an intervention. Its 9,261 participants enrollment target places it among the larger protocols in the corpus, below the 100,599-participant average among 7 other Age-related Macular Degeneration (AMD) trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Age-related Macular Degeneration (AMD) appearing as the primary indexed condition, and to 1 intervention - of which Brolucizumab is the first listed.
NCT05111743 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT05111743 about?
NCT05111743 is a clinical study titled "Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (Komodo Health)". This study was a retrospective cohort study of patients to assess the early insights into real-world safety among wet AMD patients initiating brolucizumab. Evidence was generated to describe their patient characteristics and clinical outcomes. The study was conducted using the Komodo Healthcare Map.
What is the current status of trial NCT05111743?
This trial is currently completed. The enrollment target is 9,261 participants. The study started on 2020-06-17. Estimated completion is 2020-12-18.
What conditions does trial NCT05111743 study?
This clinical trial studies the following conditions: Age-related Macular Degeneration (AMD).
What interventions are being tested in trial NCT05111743?
The interventions under investigation include: Brolucizumab (DRUG).
Who is sponsoring clinical trial NCT05111743?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05111743 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Age-related Macular Degeneration (AMD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Pivotal Trial of an Automated AI-based System for Early Diagnosis and Prediction of Late Age-related Macular Degeneration
RECRUITING
-
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
RECRUITING · Phase 3
-
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
RECRUITING · Phase 2
-
Active AMD Study to Improve Function in Veterans
RECRUITING · NA
-
Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Agerelated Macular Degeneration (AMD) Who Received Anti-VEGF Agents (IRIS Registry)
COMPLETED
-
Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Age-related Macular Degeneration (AMD) Who Received Anti-vascular Endothelial Growth Factor (VEGF) Agents (Komodo Health)
COMPLETED
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06946355 · 9,119 participants · NA
Food-based Support for Hospitalized Children and Their Families
- NCT06284408 · 9,460 participants · NA
Centralized Screening Unit (CSU) at Montefiore-Einstein
- NCT05080673 · 9,500 participants · NA
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
- NCT02000089 · 9,000 participants · Phase 3
The Cancer of the Pancreas Screening-5 CAPS5)Study
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI