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NCT05918692 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Study of BMF-500 in Adults With Acute Leukemia

A Phase 1 study of Acute Myeloid Leukemia, sponsored by Biomea Fusion.

Active
Registry status
Phase 1
Development phase
35
Enrollment target
14
Study locations

NCT05918692 is a Phase 1 study of Acute Myeloid Leukemia that is active but no longer recruiting, run by Biomea Fusion. The registered enrollment target is 35 participants, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (70% lower). The trial reports 14 study locations across 12 states.

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The verdict

NCT05918692, a Phase 1 study of Acute Myeloid Leukemia, is active but no longer recruiting, sponsored by Biomea Fusion.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
35 participants
Enrollment target
14
Study locations

Study Summary

A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-500, an oral FLT3 inhibitor, in adult patients with acute leukemia.

Conditions Studied

Acute Myeloid Leukemia

Interventions

  • DRUG BMF-500

Study Locations (14)

California

  • City of Hope National Medical Center - Duarte
  • University of California, San Francisco - San Francisco

Texas

  • Texas Oncology-PA USOR - Dallas
  • MD Anderson Cancer Center - Houston

Arizona

  • Mayo Clinic - Phoenix

Colorado

  • Colorado Blood Cancer Institute - Denver

Florida

  • Mayo Clinic - Jacksonville

Georgia

  • Winship Cancer Institute, Emory University - Atlanta

Illinois

  • Northwestern Memorial Hospital - Chicago

Kentucky

  • University of Kentucky - Markey Cancer Center - Lexington

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2023-07-26
Est. Completion 2026-04
Phase Phase 1

Sponsor

Biomea Fusion

9 total trials

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What the Registry Record Tells You About NCT05918692

The ClinicalTrials.gov registry entry for NCT05918692 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 116-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (70% lower). The listed sponsor is Biomea Fusion, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Acute Myeloid Leukemia appearing as the primary indexed condition, and to 1 intervention - of which BMF-500 is the first listed.

NCT05918692 reports 14 study locations spanning 12 distinct geographic areas - top geographies include California, Texas, Arizona.

Frequently Asked Questions

What is clinical trial NCT05918692 about?

NCT05918692 is a clinical study titled "A Phase 1 Study of BMF-500 in Adults With Acute Leukemia". A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-500, an oral FLT3 inhibitor, in adult patients with acute leukemia.

What is the current status of trial NCT05918692?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2023-07-26. Estimated completion is 2026-04.

What conditions does trial NCT05918692 study?

This clinical trial studies the following conditions: Acute Myeloid Leukemia.

What interventions are being tested in trial NCT05918692?

The interventions under investigation include: BMF-500 (DRUG).

Who is sponsoring clinical trial NCT05918692?

This trial is sponsored by Biomea Fusion, which has 9 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05918692 being conducted?

This trial has 14 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.