Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05913882 · ClinicalTrials.gov registry record · NA

Combined Respiratory Training in Persons With ALS

A NA study of Dysphagia and ALS, sponsored by Nova Southeastern University.

Recruiting
Registry status
NA
Development phase
34
Enrollment target
1
Study location

NCT05913882: Recruiting NA study of Dysphagia and ALS, sponsored by Nova Southeastern University.

NCT05913882 is a NA study of Dysphagia and ALS that is actively recruiting participants, run by Nova Southeastern University. The registered enrollment target is 34 participants, below the 171-participant average among 35 other Dysphagia trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05913882, a NA study of Dysphagia and ALS, is actively recruiting participants, sponsored by Nova Southeastern University.

RECRUITING
Registry status
NA
Development phase
34 participants
Enrollment target
1
Study location

Study Summary

The goal of this interventional trial is to learn about lung volume recruitment (LVR) and expiratory muscle strength training (EMST) in a total of up to 39 patients diagnosed with ALS. The following aims will be addressed: 1. Determine the impact of combined LVR and EMST on cough strength and respiratory function in individuals with ALS. 2. Determine the impact of combined LVR and EMST on patient-reported dyspnea and bulbar impairment. 3. Describe the effect of combined LVR and EMST on patient- and caregiver reported burden and quality of life.

Primary Outcome

Greatest cough measurement measured in liters/minute.

Interventions

  • DEVICE Respiratory Muscle Strength Training (LVR+EMST)

Study Locations (1)

Florida

  • Nova Southeastern University - Fort Lauderdale

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2023-08-22
Est. Completion 2026-09-30
Phase NA
Nova Southeastern University

71 total trials

What NCT05913882 shows while recruiting

NCT05913882 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 171-participant average among 35 other Dysphagia trials with a reported enrollment target (80% lower).

The record links to 3 conditions, with Dysphagia appearing as the primary indexed condition, and to 1 intervention - of which Respiratory Muscle Strength Training (LVR+EMST) is the first listed.

NCT05913882 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT05913882 about?

NCT05913882 is a clinical study titled "Combined Respiratory Training in Persons With ALS". The goal of this interventional trial is to learn about lung volume recruitment (LVR) and expiratory muscle strength training (EMST) in a total of up to 39 patients diagnosed with ALS. The following aims will be addressed: 1. Determine the impact of combined LVR and EMST on cough strength and respi...

What is the current status of trial NCT05913882?

This trial is currently recruiting. It is a NA study. The enrollment target is 34 participants. The study started on 2023-08-22. Estimated completion is 2026-09-30.

What conditions does trial NCT05913882 study?

This clinical trial studies the following conditions: Dysphagia, ALS, Respiratory Insufficiency.

What interventions are being tested in trial NCT05913882?

The interventions under investigation include: Respiratory Muscle Strength Training (LVR+EMST) (DEVICE).

Who is sponsoring clinical trial NCT05913882?

This trial is sponsored by Nova Southeastern University, which has 71 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05913882 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Dysphagia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05913882's enrollment target sits among peer trials

34 28th of 35 higher than 8 of 35 other Dysphagia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Dysphagia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02897063 · 34 participants · Phase 1

    Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

  • NCT03906617 · 34 participants · Phase 4

    Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine

  • NCT03992378 · 34 participants · NA

    Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis

  • NCT04047849 · 34 participants · Phase 4

    Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05913882, the US trial registry maintained by the National Library of Medicine. NCT05913882 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.