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Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD
NCT05904028 · View on ClinicalTrials.gov ↗
Study Summary
Home optical coherence tomography- guided treatment versus treat and extend for the management of neovascular age-related macular degeneration.
Conditions Studied
Interventions
- DRUG Intravitreal injections of 6 mg faricimab on a Treat and Extend schedule
- DEVICE Intravitreal injections of 6 mg faricimab on a home optical coherence tomography-guided treatment schedule
Study Locations (20)
Florida
- National Ophthalmic Research Institute — Fort Myers
- National Ophthalmic Research Institute — Fort Myers
- University of Florida- Jacksonville — Jacksonville
- Florida Retina Institute, James A. Staman, MD, PA- Jacksonville — Jacksonville
- Argus Research Center, Inc — Naples
- Southeast Eye Institute, P.A. dba Eye Associates of Pinellas — Pinellas Park
- Retina Associates of Sarasota — Sarasota
- Sarasota Retina Institute — Sarasota
- Retina Associates of Florida, LLC — Tampa
California
- Kent W. Small, MD, AMC — Glendale
- Loma Linda University — Loma Linda
- East Bay Retina Consultants, Inc. — Oakland
- Kaiser Permanente - Oakland — Oakland
- Southern California Desert Retina Consultants, Inc. — Palm Desert
- UC Davis Health Eye Center — Sacramento
- Macula Retina Vitreous Institute — Torrance
- Bay Area Retina Associates A Medical Group — Walnut Creek
Georgia
- Southeast Retina Center, P.C. — Augusta
- Thomas Eye Group — Sandy Springs
Connecticut
- Retina Consultants — Manchester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2023-11-09 |
| Est. Completion | 2027-07-30 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05904028
The ClinicalTrials.gov registry entry for NCT05904028 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jaeb Center for Health Research, which has 134 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Neovascular Age-related Macular Degeneration appearing as the primary indexed condition, and to 2 interventions — of which Intravitreal injections of 6 mg faricimab on a Treat and Extend schedule is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05904028 reports 20 study locations spanning 4 distinct geographic areas — top geographies include Florida, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05904028 about?
NCT05904028 is a clinical study titled "Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD". Home optical coherence tomography- guided treatment versus treat and extend for the management of neovascular age-related macular degeneration.
What is the current status of trial NCT05904028?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 600 participants. The study started on 2023-11-09. Estimated completion is 2027-07-30.
What conditions does trial NCT05904028 study?
This clinical trial studies the following conditions: Neovascular Age-related Macular Degeneration. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05904028?
The interventions under investigation include: Intravitreal injections of 6 mg faricimab on a Treat and Extend schedule (DRUG), Intravitreal injections of 6 mg faricimab on a home optical coherence tomography-guided treatment schedule (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05904028?
This trial is sponsored by Jaeb Center for Health Research, which has 134 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05904028 being conducted?
This trial has 20 study locations across California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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