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NCT05890183 · ClinicalTrials.gov registry record · NA
Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode
A NA study of Schizophrenia and Schizoaffective Disorder, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05890183 is a NA study of Schizophrenia and Schizoaffective Disorder that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 100 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (54% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05890183, a NA study of Schizophrenia and Schizoaffective Disorder, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The participants in the study will receive psychiatric treatment at the UCLA Aftercare Research Program. All participants in this 12-month RCT will receive cognitive training. Half of the patients will also be randomly assigned to the aerobic exercise and strength training condition, and the other half will be randomly assigned to the Healthy Living Group condition. The primary outcome measures are improvement in cognition and level of engagement in the in-group and at-home exercise sessions. Increases in the level of the patient's serum brain-derived neurotropic factor (specifically Mature BDNF) which causes greater brain neuroplasticity and is indicator of engagement in aerobic exercise, will be measured early in the treatment phase in order to confirm engagement of this target. In order to demonstrate the feasibility and portability of this intervention outside of academic research programs, the interventions will be provided via videoconferencing. The proposed study will incorporate additional methods to maximize participation in the exercise condition, including the use of the Moderated Online Social Therapy (MOST) platform to enhance motivation for treatment based on Self-Determination Theory principles, and a "bridging" group to help the participants generalize gains to everyday functioning. In addition, the exercise group participants will receive personally tailored text reminders to exercise.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive training
- BEHAVIORAL Aerobic Exercise Program
- BEHAVIORAL Moderated Online Social Therapy (MOST)
- BEHAVIORAL Chorus Participatory Text Messaging Program
- BEHAVIORAL Healthy Living Group (HLG)
Study Locations (1)
California
- UCLA Aftercare Research Program - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-05-23 |
| Est. Completion | 2028-05-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05890183
The ClinicalTrials.gov registry entry for NCT05890183 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (54% lower). The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Schizophrenia appearing as the primary indexed condition, and to 5 interventions - of which Cognitive training is the first listed.
NCT05890183 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05890183 about?
NCT05890183 is a clinical study titled "Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode". The participants in the study will receive psychiatric treatment at the UCLA Aftercare Research Program. All participants in this 12-month RCT will receive cognitive training. Half of the patients will also be randomly assigned to the aerobic exercise and strength training condition, and the other h...
What is the current status of trial NCT05890183?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2023-05-23. Estimated completion is 2028-05-31.
What conditions does trial NCT05890183 study?
This clinical trial studies the following conditions: Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder.
What interventions are being tested in trial NCT05890183?
The interventions under investigation include: Cognitive training (BEHAVIORAL), Aerobic Exercise Program (BEHAVIORAL), Moderated Online Social Therapy (MOST) (BEHAVIORAL), Chorus Participatory Text Messaging Program (BEHAVIORAL), Healthy Living Group (HLG) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05890183?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05890183 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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