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ACTIVE NOT RECRUITING Phase 1

A Study of CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hodgkin Lymphoma (B-NHL)

NCT05879744 · View on ClinicalTrials.gov ↗

Study Summary

CLN-978-001 is a Phase 1, open-label, dose escalation and dose expansion study of CLN-978 in patients with Relapse/Refractory (R/R) B-cell Non-Hodgkin Lymphoma (B-NHL).

Conditions Studied

Interventions

  • DRUG CLN-978

Study Locations (6)

Alabama

  • University of Alabama at Birmingham — Birmingham

California

  • City of Hope — Duarte

Georgia

  • Winship Cancer Institute at Emory University — Atlanta

Massachusetts

  • Massachusetts General Hospital — Boston

New Jersey

  • Hackensack University Medical Center — Hackensack

Texas

  • University of Texas Southwestern Medical Center — Dallas

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2023-05-31
Est. Completion 2027-04
Phase Phase 1

Sponsor

Cullinan Therapeutics

35 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05879744

The ClinicalTrials.gov registry entry for NCT05879744 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cullinan Therapeutics, which has 35 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with NHL appearing as the primary indexed condition, and to 1 intervention — of which CLN-978 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05879744 reports 6 study locations spanning 6 distinct geographic areas — top geographies include Alabama, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05879744 about?

NCT05879744 is a clinical study titled "A Study of CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hodgkin Lymphoma (B-NHL)". CLN-978-001 is a Phase 1, open-label, dose escalation and dose expansion study of CLN-978 in patients with Relapse/Refractory (R/R) B-cell Non-Hodgkin Lymphoma (B-NHL).

What is the current status of trial NCT05879744?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 90 participants. The study started on 2023-05-31. Estimated completion is 2027-04.

What conditions does trial NCT05879744 study?

This clinical trial studies the following conditions: NHL, NHL, Relapsed, Adult. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05879744?

The interventions under investigation include: CLN-978 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05879744?

This trial is sponsored by Cullinan Therapeutics, which has 35 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05879744 being conducted?

This trial has 6 study locations across Alabama, California, Georgia, Massachusetts, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial